血管新生
EGFR
(236)
Syk
(34)
JAK
(150)
FLT
(111)
VDA
(2)
HER
(57)
FGFR
(94)
BTK
(67)
Bcr-Abl
(71)
ALK
(70)
VEGFR
(200)
FAK
(41)
PDGFR
(108)
HIF
(62)
Src
(113)
アポトーシス
Caspase
(166)
p53
(70)
Necroptosis
(3)
ASK
(9)
Apoptosis
(1268)
TNF
(245)
RIP kinase
(32)
Mdm2
(33)
IAP
(22)
PD-1/PD-L1
(28)
c-RET
(42)
BCL
(153)
OXPHOS
(5)
FOXO1
(2)
DAPK
(5)
Pyroptosis
(5)
Fas/FasL
(3)
Survivin
(6)
Ferroptosis
(108)
PERK
(25)
オートファジー
細胞周期・チェックポイント
PD-1/PD-L1
(28)
PLK
(32)
ROCK
(55)
Rho
(28)
KSP
(4)
DHFR
(22)
IRE1
(17)
DUB
(55)
Wee1
(8)
Chk
(36)
Aurora Kinase
(68)
c-Myc
(27)
DYRK
(22)
Haspin Kinase
(3)
BMI-1
(6)
LIM Kinase
(8)
Antifolate
(19)
cell cycle arrest
(5)
APC
(8)
Serine/threonin kinase
(44)
Nucleoside Antimetabolite...
(91)
DNA/RNA Synthesis
(306)
CDK
(289)
クロマチン・エピジェネティック
Histone Demethylase
(65)
HIF/HIF Prolyl-Hydroxylas...
(58)
PARP
(116)
Pim
(27)
Histone Methyltransferase
(155)
Epigenetic Reader Domain
(214)
Sirtuin
(74)
HIF
(62)
JAK
(150)
DNA Methyltransferase
(32)
Aurora Kinase
(68)
Histone Acetyltransferase
(34)
AMPK
(109)
HDAC
(142)
PKC
(133)
Methionine Adenosyltransf...
(8)
PAD
(9)
細胞骨格シグナル
Dynamin
(9)
Integrin
(63)
HSP
(91)
PKC
(133)
Gap Junction Protein
(12)
Microtubule Associated
(156)
Myosin
(16)
Akt
(172)
Bcr-Abl
(71)
ROCK
(55)
FAK
(41)
Wnt/beta-catenin
(126)
Arp2/3 Complex
(1)
PAK
(19)
Kinesin
(33)
DNA損傷・DNA修復
Topoisomerase
(141)
DNA Alkylation
(25)
Telomerase
(18)
DNA-PK
(40)
BMI-1
(6)
DNA/RNA Synthesis
(306)
HDAC
(142)
DNA
(24)
PARP
(116)
CRISPR/Cas9
(7)
DNA gyrase
(16)
Nucleoside Antimetabolite...
(91)
DNA Alkylator/Crosslinker
(33)
MTH1
(6)
DHFR
(22)
PPAR
(177)
Sirtuin
(74)
ATM/ATR
(33)
DUB
(55)
内分泌・ホルモン
Oxytocin Receptor
(8)
Estrogen/progestogen Rece...
(130)
Androgen Receptor
(97)
Thyroid hormone receptor(...
(33)
GPR
(130)
Estrogen Receptor/ERR
(115)
Glucocorticoid Receptor
(84)
RAAS
(115)
Opioid Receptor
(135)
Aromatase
(24)
Reductase
(40)
LHRH
(2)
GPCR/Gタンパク質
Melanocortin Receptor
(25)
Prostaglandin Receptor
(165)
Histamine Receptor
(216)
Adenosine Receptor
(100)
Neuropeptide Y Receptor
(40)
Melatonin Receptor
(10)
Bombesin Receptor
(11)
LPL Receptor
(39)
GHSR
(18)
Amylin Receptor
(3)
GPCR19
(14)
Endothelin Receptor
(26)
TSH Receptor
(5)
Protease-activated Recept...
(34)
Hedgehog/Smoothened
(36)
Neurokinin receptor
(54)
OX Receptor
(23)
Glucagon Receptor
(49)
PAFR
(36)
Neuropeptide W
(1)
CGRP Receptor
(12)
GTPase
(15)
LPA Receptor
(20)
Neurotensin Receptor
(17)
CXCR
(57)
CaSR
(15)
Adrenergic Receptor
(324)
Ras
(97)
5-HT Receptor
(489)
CRFR
(15)
Adiponectin receptor
(4)
Apelin receptor
(10)
Motilin Receptor
(2)
P2Y Receptor
(21)
GPR
(130)
Somatostatin
(16)
Sigma receptor
(38)
EBI2/GPR183
(3)
Cannabinoid Receptor
(80)
Guanylate cyclase
(21)
Bradykinin Receptor
(22)
cAMP
(38)
Leukotriene Receptor
(18)
Dopamine Receptor
(290)
Oxytocin Receptor
(8)
Vasopressin Receptor
(21)
Annexin A
(7)
GNRH Receptor
(23)
cholecystokinin
(22)
SGLT
(31)
S1P Receptor
(45)
GRK
(11)
Melanin-concentrating Hor...
(10)
Opioid Receptor
(135)
免疫・炎症
TLR
(84)
NO Synthase
(105)
Thrombopoietin Receptor
(4)
CD73
(4)
Reactive Oxygen Species
(191)
Cell wall
(7)
Pyroptosis
(5)
cGAS
(5)
IFNAR
(11)
MALT
(6)
gp120/CD4
(7)
Arginase
(8)
NOS
(114)
Histamine Receptor
(216)
Galectin
(5)
IL Receptor
(199)
Complement System
(29)
Aryl Hydrocarbon Receptor
(26)
AIM2
(3)
CD38
(4)
Immunology/Inflammation r...
(50)
COX
(375)
MRP
(26)
LTR
(34)
PGE Synthase
(15)
Nrf2
(76)
NOD-like Receptor (NLR)
(18)
CXCR
(57)
STING
(23)
NADPH-oxidase
(37)
Antiviral
(80)
AhR
(22)
NOD
(30)
ROS
(128)
IRAK
(21)
MyD88
(7)
CCR
(67)
FLAP
(6)
PD-1/PD-L1
(28)
Interleukin
(50)
Prostaglandin Receptor
(165)
JAK・STATシグナル
MAPK
S6 Kinase
(37)
TOPK
(7)
Ras
(97)
ERK
(173)
MNK
(8)
Raf
(93)
KLF
(3)
MAPK
(82)
p38 MAPK
(161)
JNK
(102)
MLK
(11)
MEK
(65)
膜輸送体・イオンチャネル
Proton pump
(38)
Chloride channel
(34)
CRM1
(8)
Aquaporin
(6)
Calcium Channel
(291)
ABC
(20)
BCRP
(12)
Sodium Channel
(186)
VDAC
(6)
Monoamine Transporter
(14)
Na-K-Cl cotransporter
(5)
Anion Exchanger
(1)
NPC1L1
(7)
Potassium Channel
(245)
iGluR
(98)
OCT
(8)
ATPase
(98)
P-gp
(69)
OAT
(7)
Monocarboxylate transport...
(11)
Na+/Ca2+ Exchanger
(8)
CFTR
(26)
Piezo Channel
(3)
GABA Receptor
(200)
TRP/TRPV Channel
(142)
HCN Channel
(3)
P2X Receptor
(45)
代謝
Phosphorylase
(12)
GSNOR
(2)
Reductase
(40)
Acyltransferase
(29)
Transferase
(57)
NAMPT
(13)
Fatty Acid Synthase
(44)
LDL
(23)
Glucokinase
(36)
N-Acetylglucosaminyltrans...
(1)
Drug Metabolite
(61)
ROR
(33)
hCE
(2)
Angiotensin-converting En...
(6)
Mitochondrial Metabolism
(66)
Phosphatase
(132)
DHFR
(22)
Procollagen C Proteinase
(1)
Glutathione Peroxidase
(24)
PDE
(213)
NUDIX hydrolase
(2)
FXR
(29)
Reactive Oxygen Species
(191)
Carbonic Anhydrase
(50)
Thioredoxin
(1)
AhR
(22)
HIF/HIF Prolyl-Hydroxylas...
(58)
HSP
(91)
Amino Acids and Derivativ...
(40)
Hydrogenase
(1)
Stearoyl-CoA Desaturase (...
(12)
Aminopeptidase
(15)
UGT
(11)
MAGL
(6)
P450
(224)
Liver X Receptor
(22)
ATP Citrate Lyase
(9)
Lipase
(24)
HMG-CoA Reductase
(27)
Decarboxylase
(6)
PKM
(10)
Transaminase
(3)
PPAR
(177)
Acetyl-CoA Carboxylase
(11)
Lipid
(18)
Xanthine Oxidase
(24)
Indoleamine 2,3-Dioxygena...
(24)
Taste receptor
(2)
transporter
(41)
NEDD8
(4)
Retinoid Receptor
(50)
IDO
(22)
PAI-1
(12)
Prolyl Endopeptidase (PR...
(2)
Phospholipase
(81)
Isocitrate Dehydrogenase ...
(11)
NADPH
(33)
Endogenous Metabolite
(1239)
RAR/RXR
(5)
Dehydrogenase
(182)
Neprilysin
(9)
Calcium Channel
(291)
Amylase
(7)
Casein Kinase
(50)
FABP
(4)
glycosidase
(1)
Hexokinase
(3)
SGK
(10)
Serine/threonin kinase
(44)
Factor Xa
(24)
stilbene oxidase
(1)
MAO
(88)
FAAH
(33)
aconitase
(1)
Lipoxygenase
(84)
CPT
(2)
CETP
(16)
Hydroxylase
(24)
Adenosine deaminase
(6)
Epoxide Hydrolase
(22)
微生物学・ウィルス学
Integrase
(5)
Reverse Transcriptase
(45)
RSV
(17)
Antibiotic
(621)
SARS-CoV
(101)
Influenza Virus
(166)
HIV Protease
(303)
Antifungal
(334)
GluCls
(3)
ribosome
(36)
HBV
(84)
Virus Protease
(84)
Parasite
(319)
CCR
(67)
HSV
(83)
Antifection
(416)
Anti-infection
(67)
Antibacterial
(1076)
HCV Protease
(123)
神経科学
COX
(375)
AChR
(411)
NMU2R
(1)
P-gp
(69)
OX Receptor
(23)
AChE
(112)
NMDAR
(96)
Norepinephrine
(44)
Beta-Secretase
(17)
Neuropeptide W
(1)
iGluR
(98)
Melanocortin Receptor
(25)
5-HT Receptor
(489)
Gamma-secretase
(46)
Histamine Receptor
(216)
GlyT
(12)
BACE
(35)
Monoamine Oxidase
(49)
Neurokinin receptor
(54)
Adrenergic Receptor
(324)
FAAH
(33)
Dopamine Receptor
(290)
GluR
(159)
GABA Receptor
(200)
MT Receptor
(9)
CGRP Receptor
(12)
AAK1 (AP2 associated kina...
(6)
Serotonin Transporter
(43)
MAO
(88)
Neuropeptide Y Receptor
(40)
P2Y Receptor
(21)
Opioid Receptor
(135)
CaMK
(44)
Adenylyl cyclase
(9)
Beta Amyloid
(93)
Adenosine Receptor
(100)
P2X Receptor
(45)
Imidazoline Receptor
(10)
NF-Κb
IκB/IKK
(73)
Reactive Oxygen Species
(191)
NF-κB
(382)
RANKL/RANK
(6)
IRAK
(21)
NOD
(30)
RIP kinase
(32)
酸化還元
PI3K/Akt/mTORシグナル
PI3K
(266)
DNA-PK
(40)
PTEN
(9)
Akt
(172)
PI4K
(17)
S6 Kinase
(37)
mTOR
(127)
ATM/ATR
(33)
GSK-3
(99)
PDK
(24)
AMPK
(109)
SIK
(7)
MELK
(8)
プロテアーゼ・プロテアソーム
Protease
(2)
Proteasome
(81)
Caspase
(166)
DPP-4
(27)
Prolyl Endopeptidase (PR...
(2)
HCV Protease
(123)
Carboxypeptidase
(7)
Thrombin
(38)
Tyrosinase
(99)
Glutaminase
(8)
MMP
(125)
HIV Protease
(303)
Gamma-secretase
(46)
Cysteine Protease
(49)
Serine Protease
(46)
幹細胞
STAT
(123)
ROCK
(55)
Porcupine
(8)
YAP
(16)
Casein Kinase
(50)
GSK-3
(99)
Stemness kinase
(1)
Hippo pathway
(5)
Wnt/beta-catenin
(126)
TGF-beta/Smad
(69)
Smo
(22)
Gamma-secretase
(46)
JAK
(150)
Hedgehog/Smoothened
(36)
チロシンキナーゼ・アダプター
Src
(113)
PDGFR
(108)
TAM Receptor
(42)
c-Fms
(34)
PYK2
(6)
Syk
(34)
FAK
(41)
PKA
(62)
CSF-1R
(16)
ALK
(70)
Tie-2
(7)
ROS Kinase
(13)
ACK
(5)
DYRK
(22)
Discoidin Domain Receptor...
(12)
FGFR
(94)
EGFR
(236)
FLT
(111)
Bcr-Abl
(71)
Hck
(4)
BTK
(67)
HER
(57)
Ephrin Receptor
(15)
c-Met/HGFR
(83)
VEGFR
(200)
c-RET
(42)
IGF-1R
(51)
Trk receptor
(43)
c-Kit
(83)
Tyrosine Kinases
(56)
ユビキチン
その他
Decarboxylase
(6)
Progesterone Receptor
(30)
Platelet aggregation
(25)
CYP19A1
(1)
Others
(15607)
Fer/FerT kinase
(1)
advanced glycation end pr...
(4)
DprE1
(5)