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Search Results for " Tazemetostat trihydrochloride "

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カタログ番号 製品名 別名 ターゲット
T15240 Tazemetostat trihydrochloride EPZ-6438 trihydrochloride,E-7438 trihydrochloride Histone Methyltransferase
Tazemetostat trihydrochloride is a selective and orally available inhibitor of EZH2 (IC50: 4 nM for rat EZH2). It inhibits the activity of human PRC2-containing wild-type EZH2 (Ki: 2.5 nM). It inhibits EZH2 (IC50s: 11 an...
T17002 Tazemetostat hydrobromide E-7438 hydrobromide,EPZ-6438 hydrobromide Histone Methyltransferase
Tazemetostat hydrobromide (E-7438 hydrobromide) is a potent and selective EZH2 inhibitor. Tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 (Ki: 2.5 n...
T1788 Tazemetostat E-7438,EPZ6438 Histone Methyltransferase
Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epith...
T70588 Tazemetostat HCl
Tazemetostat HCl is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. EPZ-6438 induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Treatment of...