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Search Results for " hepatic damage "

ターゲット

6

阻害剤

7

天然化合物

1

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T5045 GSK4112 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452 Autophagy
GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.
T34757 Symphytine
Symphytine is a natural inducer of hepatic tumors. Symphytine interacts with DNA in liver endothelial cells and hepatocytes, resulting in DNA damage, mutation induction, and cancer development.
T83900 12β-Hydroxyisocholic Acid LCA,Lagocholic Acid
12β-Hydroxyisocholic acid, a bile acid and an isomer of cholic acid, exhibits increased hepatic levels in a mouse model of alcoholic liver damage.
T76498 H-Leu-Ser-Lys-Leu-OH
H-Leu-Ser-Lys-Leu-OH (LSYL), a latency-associated peptide located at the amino terminus of LAP, exhibits an inhibitory effect on TGF-β1 activation. By binding with KRFK, it obstructs TGF-β1 signal transduction, thereby i...
T72017 6(5H)-Phenanthridinone
6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κ...
T83682 Tat-Gap 19 TFA
Tat-Gap 19, a peptide inhibitor of connexin43 (Cx43) hemichannels, is derived from the HIV-1 Tat protein transduction domain fused with a nine-amino acid sequence from Cx43 residues 128-136. This compound, at a concentra...
カタログ番号 製品名 別名 ターゲット
TN1599 Eburicoic acid Eburicoicacid,MFCD00238594,ZINC4655149 Antioxidant , TNF , NOS , NO Synthase , CCR , Immunology/Inflammation related
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in studies about anti-liver cancer.
T3414 Morroniside Apoptosis , MMP , Pyroptosis
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...
T4S0797 Berberine Berberin,Umbellatine Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
TMA1409 Cis-Mulberroside A TNF , NOS
cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage.
TN6570 Daturaolone
Daturaolone has potency in reducing the harmful effects or in maintaining the normal hepatic physiological mechanisms in both acute and chronic hepato-toxic induced liver damage in rats. Daturaolone also possesses in viv...
T82365 Fulvotomentoside B
Fulvotomentoside B, a saponin derived from Lactobacillus flavus, displays hepatoprotective properties. It notably decreases serum glutamate pyruvate transaminase (SGPT) and triacylglycerol (GT) concentrations in mice sub...
T35624 Ajoene
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00817 HO-1 Protein, Human, Recombinant Human E. coli
Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to ...