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Search Results for " phosphodiesterase inhibitor "

299

阻害剤

32

天然化合物

カタログ番号 製品名 別名 ターゲット
T36018 Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
T10676 Carbodenafil PDE
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).
T12150 N-Methylbenzamide PDE
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.
T6462 Deltarasin PDE , Ras
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.
T27172 Difamilast PDE
Difamilast is an inhibitor of phosphodiesterase IV.
T2129 Zaprinast PDE
Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through a...
T10410 ATX inhibitor 1 PDE
ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).
T7954 YM976 PDE
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
T6054 GSK256066 PDE
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
T21965 MBCQ PDE
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
T27475 GSK356278 GSK-356278,GSK 356278 PDE
GSK356278 is an effective and selective inhibitor of phosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory, anxiolytic, and cognitio...
T7888 Enpp-1-IN-1 PDE
Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)
T4695 CP671305 PDE
CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.
T0160 Anagrelide Anagrelida,Xagrid,Anagrelidum PDE
Anagrelide (Xagrid) is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor. The physiologic effect of anagrelide is by means of Decreased Platelet Production.
T3631 PF-8380 PDE
PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhib...
T12267 NSP-805 PDE
NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.
T5106 BRL-50481 PDE
BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.
T5496 ML-030 PDE
ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively)
T2646 HA130 PDE
HA130 is a selective ATX (autotaxin) inhibitor.
T13448 (R)-(-)-Rolipram (R)-Rolipram,(-)-Rolipram DNA-PK , Others
(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.
T4462 Roflumilast N-oxide PDE
Roflumilast N-oxide is an inhibitor of PDE type 4.
T1618 Dipyridamole Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine PDE
Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.
T5474 D159687 D 159687 PDE
D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant or anxiolytic benefit.
T4041 Ziritaxestat GLPG1690 PDE
Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.
T7346 Lodenafil Hydroxyhomosildenafil PDE
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
T10590 Zatolmilast BPN14770 Others , PDE
Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
T1096 Milrinone Win 47203 PDE
Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.
T6548 Irsogladine Dicloguamine PDE , AChR
Irsogladine (Dicloguamine) is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.
T12913 Siguazodan SKF 94836 PDE
T8515 Osoresnontrine BI-409306 PDE
Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.
T6649 (S)-(+)-Rolipram (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram Apoptosis , PDE
(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
T6147 Nortadalafil Demethyl Tadalafil PDE
Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
T6445 Cilomilast SB-207499,Ariflo PDE
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
T8919 Homo Sildenafil PDE
Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.
T16499 Mardepodect PF-2545920 PDE
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodie...
T7542 Amino Tadalafil PDE
Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.
T8506 THPP-1 PDE
THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).
T21865 BC 11-38 PDE
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).
T3465 Vesnarinone OPC-8212,Arkin,Piteranometozine HIV Protease , PDE
Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cel...
T11689 ITI-214 ITI214 PDE
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...
T1745 Balipodect TAK063,TAK-063,TAK 063 PDE
Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.
T5033 Olprinone Loprinone PDE
Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output ...
T5101 BW-A 78U BW-A78U PDE
BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.
T9805 BAY 2666605 PDE
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.
T15381 Gisadenafil UK-369003 PDE
Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.
T5956 VP3.15 dihydrobromide GSK-3 , PDE
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM , 0.88 μM,respectively.)
T23154 Piclamilast RPR 73401,RP 73401 PDE
Piclamilast (RP 73401) is a PDE4 inhibitor.
T24656 PQ-10 A844337,PQ 10,A-844337,A 844337 PDE
PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
T21389 Enprofylline Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum Others
Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick...
T22086 HA 155 Autotaxin Inhibitor IV PDE
HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.

Compounds

Phosphodiesterase 4 Inhibitor
T36018
Synonym:
Target:
Carbodenafil
T10676
Synonym:
Target: PDE
N-Methylbenzamide
T12150
Synonym:
Target: PDE
Deltarasin
T6462
Synonym:
Target: PDE, Ras
Difamilast
T27172
Synonym:
Target: PDE
Zaprinast
T2129
Synonym:
Target: PDE
ATX inhibitor 1
T10410
Synonym:
Target: PDE
YM976
T7954
Synonym:
Target: PDE
GSK256066
T6054
Synonym:
Target: PDE
MBCQ
T21965
Synonym:
Target: PDE
GSK356278
T27475
Synonym: GSK-356278,GSK 356278
Target: PDE
Enpp-1-IN-1
T7888
Synonym:
Target: PDE
CP671305
T4695
Synonym:
Target: PDE
Anagrelide
T0160
Synonym: Anagrelida,Xagrid,Anagrelidum
Target: PDE
PF-8380
T3631
Synonym:
Target: PDE
NSP-805
T12267
Synonym:
Target: PDE
BRL-50481
T5106
Synonym:
Target: PDE
ML-030
T5496
Synonym:
Target: PDE
HA130
T2646
Synonym:
Target: PDE
(R)-(-)-Rolipram
T13448
Synonym: (R)-Rolipram,(-)-Rolipram
Target: DNA-PK, Others
Roflumilast N-oxide
T4462
Synonym:
Target: PDE
Dipyridamole
T1618
Synonym: Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine
Target: PDE
D159687
T5474
Synonym: D 159687
Target: PDE
Ziritaxestat
T4041
Synonym: GLPG1690
Target: PDE
Lodenafil
T7346
Synonym: Hydroxyhomosildenafil
Target: PDE
Zatolmilast
T10590
Synonym: BPN14770
Target: Others, PDE
Milrinone
T1096
Synonym: Win 47203
Target: PDE
Irsogladine
T6548
Synonym: Dicloguamine
Target: PDE, AChR
Siguazodan
T12913
Synonym: SKF 94836
Target: PDE
Osoresnontrine
T8515
Synonym: BI-409306
Target: PDE
(S)-(+)-Rolipram
T6649
Synonym: (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram
Target: Apoptosis, PDE
Nortadalafil
T6147
Synonym: Demethyl Tadalafil
Target: PDE
Cilomilast
T6445
Synonym: SB-207499,Ariflo
Target: PDE
Homo Sildenafil
T8919
Synonym:
Target: PDE
Mardepodect
T16499
Synonym: PF-2545920
Target: PDE
Amino Tadalafil
T7542
Synonym:
Target: PDE
THPP-1
T8506
Synonym:
Target: PDE
BC 11-38
T21865
Synonym:
Target: PDE
Vesnarinone
T3465
Synonym: OPC-8212,Arkin,Piteranometozine
Target: HIV Protease, PDE
ITI-214
T11689
Synonym: ITI214
Target: PDE
Balipodect
T1745
Synonym: TAK063,TAK-063,TAK 063
Target: PDE
Olprinone
T5033
Synonym: Loprinone
Target: PDE
BW-A 78U
T5101
Synonym: BW-A78U
Target: PDE
BAY 2666605
T9805
Synonym:
Target: PDE
Gisadenafil
T15381
Synonym: UK-369003
Target: PDE
VP3.15 dihydrobromide
T5956
Synonym:
Target: GSK-3, PDE
Piclamilast
T23154
Synonym: RPR 73401,RP 73401
Target: PDE
PQ-10
T24656
Synonym: A844337,PQ 10,A-844337,A 844337
Target: PDE
Enprofylline
T21389
Synonym: Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum
Target: Others
HA 155
T22086
Synonym: Autotaxin Inhibitor IV
Target: PDE
1 2 3 4 5 6
カタログ番号 製品名 別名 ターゲット
TN1266 3-O-Methylquercetin IL Receptor , cAMP , PDE
3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value; it inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentr...
T8787 Drotaverine hydrochloride PDE
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...
T1681 Aminophylline Phyllocontin PDE , Adenosine Receptor
Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor giving a bronchodilatory effect.
TN1416 Ayanin IL Receptor , P450 , PARP , PDE
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...
TN2159 Robustine PDE
Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.
T7027 EURYCOMANONE Pasakbumin A Others
Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell p...
T0892 Diphylline Dyphylline,Diprophylline PDE , Adenosine Receptor
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...
T2855 Icariin Ieariline PDE , PPAR , Autophagy
Icariin (Ieariline) is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator.
T3783 Fraxin Fraxoside,Fraxetin-8-O-glucoside,Paviin OAT , transporter , PDE
Fraxin (Fraxoside) is a glucoside of fraxetin.
T0480 Doxofylline Doxophylline PDE , Adenosine Receptor
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s...
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T6427 Butein 2’,3,4,4’-tetrahydroxy Chalcone Apoptosis , EGFR , Others , PDE , Autophagy
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
T2205 Acefylline Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid TNF , PAD , PKA , HDAC , PDE , Adenosine Receptor
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation Etanautine to help...
T0167 Vinpocetine RGH-4405,Ethyl apovincaminate IκB/IKK , NF-κB , Sodium Channel , PDE
Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
T5S2059 Glaucine Calcium Channel , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , PDE
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h...
T0070 Pentoxifylline Oxpentifylline,PTX,BL-191 HIV Protease , PDE , Adenosine Receptor , Autophagy
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...
T17199 Udenafil PDE
Udenafil is an inhibitor of PDE5 .
T4S0792 Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside Others
(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia. It exhibits antioxidative, antihypertensive activities, and acts as an inhibitor of cyclic adenosine monophosp...
TN2217 Sophoflavescenol Others , Beta-Secretase , BACE , PDE , AChR , AChE
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity witho...
T5940 Proxyphylline 7-(2-Hydroxypropyl)theophylline PDE , Adenosine Receptor
Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.
T4973 Paraxanthine 1,7-DIMETHYLXANTHINE Endogenous Metabolite
Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...
TN3013 4,5-Dimethoxycanthin-6-one Methylnigakinone P450 , Antibacterial , PDE
4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae).4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity.4,5...
T28019 (-)-Mesembrine Mesembrin,Mesembrine,Mesembranone
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).
TN2974 3-O-Methylquercetin tetraacetate IL Receptor , TNF , PDE
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness.
TN1504 Citreorosein cAMP , NF-κB , PI3K
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation an...
TN1843 Kushenol K PDE , HSV
Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus t...
T16397 Ophiobolin A Others
Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and antica...
TN4433 Licoarylcoumarin cAMP , HIV Protease , Antifection
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effe...
TN3537 Braylin IL Receptor , TNF , NF-κB
Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB. Braylin is also ...
T4700 1,3,5-Trihydroxy-4-prenylxanthone
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylch...
T75486 Toddacoumalone
Toddacoumalone, a natural compound, exhibits moderate potency as an inhibitor of phosphodiesterase 4 (PDE4) and possesses traits that are not fully ideal for an agent. It has potential application in the study of inflamm...
T73857 Mesembrine
Mesembrine ((+)-Mesembrine), a primary alkaloid distinguished by its aryloctahydroindole structure, acts as a potent 5-HT transporter inhibitor with an inhibition constant (K i) of 1.4 nM. Additionally, it demonstrates i...

天然物製品

3-O-Methylquercetin
TN1266
Synonym:
Target: IL Receptor, cAMP, PDE
Drotaverine hydrochloride
T8787
Synonym:
Target: PDE
Aminophylline
T1681
Synonym: Phyllocontin
Target: PDE, Adenosine Receptor
Ayanin
TN1416
Synonym:
Target: IL Receptor, P450, PARP, PDE
Robustine
TN2159
Synonym:
Target: PDE
EURYCOMANONE
T7027
Synonym: Pasakbumin A
Target: Others
Diphylline
T0892
Synonym: Dyphylline,Diprophylline
Target: PDE, Adenosine Receptor
Icariin
T2855
Synonym: Ieariline
Target: PDE, PPAR, Autophagy
Fraxin
T3783
Synonym: Fraxoside,Fraxetin-8-O-glucoside,Paviin
Target: OAT, transporter, PDE
Doxofylline
T0480
Synonym: Doxophylline
Target: PDE, Adenosine Receptor
Theophylline
T1083
Synonym: Theo-24,1,3-Dimethylxanthine
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
Butein
T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Acefylline
T2205
Synonym: Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid
Target: TNF, PAD, PKA, HDAC, PDE, Adenosine Receptor
Vinpocetine
T0167
Synonym: RGH-4405,Ethyl apovincaminate
Target: IκB/IKK, NF-κB, Sodium Channel, PDE
Glaucine
T5S2059
Synonym:
Target: Calcium Channel, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, PDE
Pentoxifylline
T0070
Synonym: Oxpentifylline,PTX,BL-191
Target: HIV Protease, PDE, Adenosine Receptor, Autophagy
Udenafil
T17199
Synonym:
Target: PDE
Pinoresinol 4-O-β-D-glucopyranoside
T4S0792
Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside
Target: Others
Sophoflavescenol
TN2217
Synonym:
Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE
Proxyphylline
T5940
Synonym: 7-(2-Hydroxypropyl)theophylline
Target: PDE, Adenosine Receptor
Paraxanthine
T4973
Synonym: 1,7-DIMETHYLXANTHINE
Target: Endogenous Metabolite
4,5-Dimethoxycanthin-6-one
TN3013
Synonym: Methylnigakinone
Target: P450, Antibacterial, PDE
(-)-Mesembrine
T28019
Synonym: Mesembrin,Mesembrine,Mesembranone
Target:
3-O-Methylquercetin tetraacetate
TN2974
Synonym:
Target: IL Receptor, TNF, PDE
Citreorosein
TN1504
Synonym:
Target: cAMP, NF-κB, PI3K
Kushenol K
TN1843
Synonym:
Target: PDE, HSV
Ophiobolin A
T16397
Synonym:
Target: Others
Licoarylcoumarin
TN4433
Synonym:
Target: cAMP, HIV Protease, Antifection
Braylin
TN3537
Synonym:
Target: IL Receptor, TNF, NF-κB
1,3,5-Trihydroxy-4-prenylxanthone
T4700
Synonym:
Target:
Toddacoumalone
T75486
Synonym:
Target:
Mesembrine
T73857
Synonym:
Target: