ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T6712 | Tyrphostin AG 879 | 148741-30-4 | 98% |
|
| Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR. | ||||
| T13178 | Toceranib | 356068-94-5 | 98% |
|
| Toceranib phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PD... | ||||
| T2456 | Tivozanib | 475108-18-0 | 98% |
|
| Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplasti... | ||||
| T8541 | Lenvatinib mesylate | 857890-39-2 | 98% |
|
| Lenvatinib mesylate is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. | ||||
| T1895 | SKLB 610 | 1125780-41-7 | 98% |
|
| SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, a... | ||||
| T16947 | SU16f | 251356-45-3 | 98% |
|
| SU16f is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRβ receptor by S... | ||||
| T6230 | Imatinib | 152459-95-5 | 98% |
|
| matinib is an inhibitor of the receptor tyrosine kinases c-Abl, Bcr-Abl, PDGFR, and c-Kit (IC50: 600/100/100 nM). | ||||
| T1792L | Regorafenib monohydrate | 1019206-88-2 | 98% |
|
| Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR... | ||||
| T6930 | Pazopanib Hydrochloride | 635702-64-6 | 98% |
|
| Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 7... | ||||
| TN1969 | N-(p-Coumaroyl) serotonin | 68573-24-0 | 98% |
|
| N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemi... | ||||
| T1621 | Imatinib Mesylate | 220127-57-1 | 98% |
|
| Imatinib mesylate is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively... | ||||
| T5001 | Nintedanib esylate | 656247-18-6 | 98% |
|
| BIBF 1120 esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β | ||||
| TQ0235 | AC710 | 1351522-04-7 | 98% |
|
| AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ). | ||||
| T4320 | Flumatinib | 895519-90-1 | 98% |
|
| Flumatinib is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity. | ||||
| T3570 | SU4312 | 5812-07-7 | 98% |
|
| SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexp... | ||||
| T13156L | TG 100572 Hydrochloride | 867331-64-4 | 98% |
|
| TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1... | ||||
| T14137 | AG 1295 | 71897-07-9 | 98% |
|
| AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR. But it can n... | ||||
| T9030 | SU4984 | 186610-89-9 | 98% |
|
| SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1). | ||||
| T1991 | ZM323881 hydrochloride | 193000-39-4 | 98% |
|
| ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor. | ||||
| T7104 | Dovitinib lactate | 692737-80-7 | 98% |
|
| Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM). | ||||
