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Histone Modification Compound Library

カタログ番号 L3500
  ライブラリー構成化合物リスト   Excel SDF

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol’s Histone Modification Compound Library, a unique collection of 469 histone modification related compounds, can be used for research in histone modification and related drug screening.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
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製品概要

  • ヒストン修飾に関連する469化合物を収集した独自のライブラリーで、ハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • 構造的多様性、薬効、細胞膜透過性を有する化合物
  • NMRとHPLCにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L3500)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Epigenetic Reader Domain (150)
Histone Methyltransferase (117)
HDAC (109)
Apoptosis (64)
Sirtuin (57)
Histone Demethylase (37)
Histone Acetyltransferase (30)
Autophagy (29)
HIV Protease (10)
Mitophagy (5)
Endogenous Metabolite (4)
Histamine Receptor (4)
Influenza Virus (3)
PDE (3)
NF-κB (3)
JAK (3)
COX (3)
Parasite (3)
EGFR (3)
DNA Methyltransferase (3)
MAO (3)
PROTACs (3)
Monoamine Oxidase (3)
Dehydrogenase (3)
p53 (3)
PI3K (3)
Adenosine Receptor (3)
Wnt/beta-catenin (2)
Phosphatase (2)
Dopamine Receptor (2)
DNA/RNA Synthesis (2)
Ligands for Target Protein for PROTAC (2)
AMPK (2)
RAAS (2)
PAD (2)
PPAR (2)
HSV (2)
ERK (2)
P450 (2)
CDK (2)
Gamma-secretase (2)
Virus Protease (2)
GABA Receptor (2)
TNF (2)
5-HT Receptor (1)
Sodium Channel (1)
FLT (1)
Reverse Transcriptase (1)
AChR (1)
STAT (1)
MEK (1)
BMI-1 (1)
Ligand for E3 Ligase (1)
Tyrosinase (1)
PLK (1)
Phospholipase (1)
Carboxypeptidase (1)
Mdm2 (1)
RSV (1)
Mitochondrial Metabolism (1)
DNA-PK (1)
Ferroptosis (1)
PKA (1)
HBV (1)
Tyrosine Kinases (1)
Antifolate (1)
Caspase (1)
PKC (1)
Adrenergic Receptor (1)
Topoisomerase (1)
UGT (1)
BCL (1)
Nrf2 (1)
Reactive Oxygen Species (1)
Fatty Acid Synthase (1)
MMP (1)
mTOR (1)
Androgen Receptor (1)
Antibacterial (1)
Telomerase (1)
Akt (1)
Antiviral (1)
SARS-CoV (1)
transporter (1)
HER (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE