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Natural Product Library for HTS

カタログ番号 L6000
  ライブラリー構成化合物リスト   Excel SDF

Natural products are compounds produced by organisms in nature. Their structures and functions have been selected and optimized during the long evolutionary process of nature, resulting in highly diverse structures through different processes such as oxidation and reduction, rearrangement reaction, cationic cyclization, condensation reactions, and pericyclic reactions.

These unique chemical structures endow natural products with target-specific binding ability and good biological activity. Therefore, natural products have become an important source for drug discovery of major disease treatments. Whenever a new game-changing drug emerges, it is usually, though not every time, accompanied by the discovery of a new type of natural product, which also promotes the development of medicinal chemistry and life sciences.

TargetMol’s Natural Product Library for HTS has a collection of 4533 carefully selected natural product monomers. These natural product monomers are widely sourced, structurally diversed and highly representative. They exist in natural sources extracted and purified from more than 2,900 kinds of Chinese medicinal herbs, animals and microorganisms, covering more than 500 different scaffolds and more than 1,000 target receptors, and most of the components have reached the purity of reference standards. In addtion, the library also contains many rare natural products with extremely high unit prices, which makes the library highly cost-effective. TargetMol’s Natural Product Library for HTS is a powerful tool for drug development, pharmacological research, stem cell differentiation, fingerprint research, quality research and other fields.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
Get quote

製品概要

  • 4533 種類の高純度な天然化合物とその誘導体を独自に収集
  • 既知の生物活性を有し、創薬研究、薬理学研究、幹細胞分化、細胞認識学、品質研究などの分野でハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に使用可能
  • 明確な由来:植物、動物、微生物など単離した天然物の由来を記載
  • 多様な構造:4,320 種類の天然物は、アルカロイド、リモノイド、セスキテルペン、ジテルペン、五員環トリテルペン、ステロールなど様々な種類の構造を含有
  • 詳細な化合物情報により分子構造、溶解性、ターゲット、活性、IC50値、および生物活性が一目瞭然
  • 高いコストパフォーマンスとリーズナブルな価格設定により皆様の経費を節約

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L6000)

Publications Cited TargetMol Libraries

1. Nature Biotechnology. 2021, 39(11): 1444-1452. 2. Immunity. 2023. 3. Nature Microbiology. 2023, 8(1): 121-134. 4. Nature Communications. 2022, 13(1): 1-15.. 5. Blood. 2021, 137(11): 1478-1490. 6. Nature Communications. 2019 Apr 23;10(1):1914. 7. Nature Communications. 2020, 11(1): 1-12. 8. Acta Pharmaceutica Sinica B. 2022. 9. Protein & Cell. 2017 Aug;8(8):618-622.
10. Engineering. 2023. 11. Bone Research. 2023, 11(1): 54. 12. Cancer Immunology Research. 2023: CIR-22-0483. 13. Redox Biology. 2022: 102229. 14. Journal of Cell Biology. 2022, 221(5): e202112024. 15. Clinical Cancer Research. 2020, 26(13): 3408-3419. 16. Chemical Science. 2022. 17. Cell & Bioscience. 2021, 11(1): 1-14. 18. Cell Reports. 2023, 42(12). 19. Journal of Translational Medicine. 2022, 20(1): 1-11.. 20. Biomedicine & Pharmacotherapy. 2024, 171: 116176. 21. Acta Pharmacologica Sinica. 2022: 1-15. 22. Cell Proliferation. 2022: e13214. 23. Cell Death & Disease,. 2020, 11(9): 1-12. 24. The American Journal of Chinese Medicine. 2020: 1-20. 25. International Journal of Molecular Sciences. 2021, 22(21): 12037. 26. Journal of Agricultural and Food Chemistry. 2023. 27. Viruses. 2023, 15(4): 891. 28. Acta Pharmaceutica Sinica B. 2020. 29. Journal of Chemical Information and Modeling. 2023. 30. Frontiers in chemistry. 2022, 10. 31. Food & Function. 2018, 9(11): 5536-5546. 32. Journal of Agricultural and Food Chemistry. 2021. 33. Cell Death Discovery. 2021, 7(1): 1-10. 34. Pharmaceuticals. 2023, 16(5): 767. 35. Bioorganic Chemistry. 114 (2021): 105043. 36. European Journal of Pharmaceutical Sciences. 2023: 106672.. 37. Plants-Basel. 2024, 13(2): 318.. 38. Cancer Science. 2021, 112(11): 4722. 39. Frontiers in Pharmacology. 2020, 11. 40. Journal of Cheminformatics. 2020, 12(1): 1-51. 41. Journal of Natural Products. 2022. 42. Neoplasia. 2020, 22(4): 179-191. 43. Journal of Chemical Information and Modeling. 2018 Aug 27;58(8):1518-1532. 44. Plos one. 2023, 18(4): e0281834. 45. Virology. 2022. 46. ChemMedChem. 2022: e202100719. 47. Veterinary Microbiology. 2021 Apr;255:109016. 48. Molecules. 2020, 25(4): 938. 49. Biomolecules. 2019 Jan 24;9(2). 50. Experimental and Therapeutic Medicine. 2021, 22(2): 1-13. 51. Pharmacology. 2020: 1-7. 52. Interdisciplinary Sciences, Computational Life Sciences. 2020, 12: 368-376. 53. Springer. 2020: 1-27. 54. bioRxiv. 2023: 2023.08. 31.555687.. 55. SSRN. 2023. 56. Preprints. 2019. 57. bioRxiv. 2021. 58. STAR Protocols. 2022: 101794. 59. bioRxiv. 2022. 60. Molecular Immunology. 2022, 147: 1-9. 62. Physical Sciences Reviews. 2019, 4(6). 63. Cell Stem Cell. 2022 Apr 29(4) 545–558. 64. Science Bulletin. 2022. 65. Science Translational Medicine. 2022, 14(656): eabn3231. 66. Science Advances. 2023, 9(9): eade3760. 67. Nature. 2020, 582: 289-293. 68. Nature Communications. 2023, 14(1): 1020.. 69. Nature Communications. 2023, 14(1): 2756.. 70. Nucleic Acids Research. 2021. 71. Nature Communications. 2023, 14(1): 7574. 72. Advanced Science. 2020, 7(16): 2000925. 73. Angewandte Chemie. 2021. 74. Protein & Cell. 2021, 12(11): 877-888. 75. Pharmacology & Therapeutics. (2021): 107930. 76. Nature Communications. 2021, 12(1): 1-12. 77. Li H, Sun Y, Yin H, et al.Virtual screening of natural products targeting ubiquitin-specific protease 7.Journal of Biomolecular Structure and Dynamics.2024: 1-8. 78. Duo L, Chen Y, Liu Q, et al.Discovery of Novel SOS1 Inhibitors Using Machine Learning.RSC Medicinal Chemistry.2024 79. Li X, Xiang C, Zhu S, et al.SNX8 enables lysosome reformation and reverses lysosomal storage disorder.Nature Communications.2024, 15(1): 2553. 80. Zhao L, Zhu Y, Tao H, et al.Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation.Acta Pharmaceutica Sinica B.2024 81. Ma Y, Song Y, Wang J, et al.Discovery of novel covalent inhibitors of DJ-1 through hybrid virtual screening.Future Medicinal Chemistry.2024 (0). 82. Li Q, Zhou S, KIM H, et al.Discovering Novel Cathepsin L Inhibitors from Natural Products Using Artificial Intelligence.Computational and Structural Biotechnology Journal.2024
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化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE