Covalent Natural Product Library

カタログ番号 L6150

ライブラリー構成化合物リスト Excel SDF

Natural products have been proven to demonstrate their success in modulating certain isolated but important targets, such as a range of antimicrobial targets, in particular protein-protein interactions. Therefore, many researchers consider natural products and their derivatives as unique tools for the study and manipulation of protein function.

Covalent compounds, a class of organic small molecules, can interact with specific target proteins and form covalent bonds, resulting in a change in protein conformation that inhibits protein activity. Except for some rare cases, protein modifications by covalent interactions are usually irreversible.

TargetMol Natural Product Covalent Library carefully screens 596 covalent compounds of natural products, which have not only the characteristics of natural products but also the mechanism of action of covalent compounds, and are cost-effective and powerful tools for drug development, pharmacological studies, stem cell differentiation, fingerprinting studies, quality studies and other fields.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。また、個人の方への販売は行っておりません。

パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM
250 μL * 10 mM

お問い合わせはこちら

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]

ライブラリ構成化合物リストを依頼する

製品概要

生物活性、薬理活性の詳細な情報および、スクリーニングにおける理論的な方向性と研究の基盤を提供
原料のソースが明確：動物、植物、微生物から既知の有効な天然物を選択、特に植物種の正確な英名とラテン名表示は後の研究で確認が容易
詳細な情報：化合物構造から溶解性、シグナル伝達経路およびターゲットから生物活性情報まで詳細な記述
コストパフォーマンス：薬剤開発の期待値が低い高価な天然化合物を排除し、高品質の天然物をより多く、より低コストで利用可能
自由度の高いカスタマイズ：天然化合物のソース、カテゴリー、研究分野、薬剤市場の状況に応じて自由な選択が可能

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
ブルーアイス同梱にて出荷

サポートファイル

ライブラリーの取扱説明書 (635 KB) TargetMol のライブラリーカタログ (13.2 MB) ExcelおよびSDFファイル形式でのライブラリー構成化合物リストの要求

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

もっと見る隠し

ライブラリーの構成

Endogenous Metabolite (111)

Apoptosis (91)

Antibacterial (69)

Autophagy (48)

NF-κB (43)

Antibiotic (43)

Reactive Oxygen Species (30)

Antifungal (24)

Antioxidant (19)

Influenza Virus (18)

COX (15)

HIV Protease (11)

Parasite (11)

Calcium Channel (10)

Dehydrogenase (10)

p38 MAPK (9)

ribosome (9)

STAT (9)

P450 (9)

Estrogen/progestogen Receptor (9)

GABA Receptor (9)

ERK (9)

Ferroptosis (9)

BCL (8)

TNF (8)

AChE (8)

MMP (8)

Akt (8)

ATPase (8)

Anti-infection (8)

NO Synthase (7)

AMPK (7)

Androgen Receptor (7)

ROS (7)

HSV (7)

Antiviral (7)

NOS (6)

PKC (6)

Caspase (6)

Glucocorticoid Receptor (6)

Microtubule Associated (6)

Progesterone Receptor (6)

HIF/HIF Prolyl-Hydroxylase (5)

Nrf2 (5)

Immunology/Inflammation related (5)

P-gp (5)

Mitophagy (5)

IL Receptor (5)

Wnt/beta-catenin (5)

SARS-CoV (5)

AChR (5)

Tyrosinase (5)

HBV (4)

DNA/RNA Synthesis (4)

Reductase (4)

Prostaglandin Receptor (4)

Virus Protease (4)

Lipoxygenase (4)

VEGFR (4)

Drug Metabolite (4)

HSP (4)

TRP/TRPV Channel (4)

Beta Amyloid (3)

Mitochondrial Metabolism (3)

Aromatase (3)

IκB/IKK (3)

JAK (3)

JNK (3)

CaMK (3)

Opioid Receptor (3)

HDAC (3)

Estrogen Receptor/ERR (3)

Epigenetic Reader Domain (3)

PPAR (3)

Sodium Channel (3)

EGFR (3)

Retinoid Receptor (3)

PI3K (3)

Proteasome (3)

Thrombin (2)

NMDAR (2)

PDE (2)

UGT (2)

p53 (2)

TGF-beta/Smad (2)

TLR (2)

Nucleoside Antimetabolite/Analog (2)

RAAS (2)

5-HT Receptor (2)

Interleukin (2)

FGFR (2)

Chloride channel (2)

HIF (2)

DNA Methyltransferase (2)

BACE (2)

iGluR (2)

Adrenergic Receptor (2)

Antifolate (2)

MAPK (2)

MAO (2)

RAR/RXR (1)

Ras (1)

Sirtuin (1)

RANKL/RANK (1)

FAK (1)

Raf (1)

Dopamine Receptor (1)

DNA gyrase (1)

CRISPR/Cas9 (1)

Serine Protease (1)

Telomerase (1)

Smo (1)

c-Met/HGFR (1)

Src (1)

Pyroptosis (1)

CDK (1)

CAT (1)

Beta-Secretase (1)

Topoisomerase (1)

Transaminase (1)

Transferase (1)

Aurora Kinase (1)

Tyrosine Kinases (1)

Antifection (1)

Acyltransferase (1)

Free radical scavengers (1)

Mdm2 (1)

PTEN (1)

PARP (1)

Monoamine Oxidase (1)

Monoamine Transporter (1)

mTOR (1)

Lipid (1)

ABC (1)

Integrin (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

IAP (1)

Histone Methyltransferase (1)

Histone Acetyltransferase (1)

Oxytocin Receptor (1)

Histamine Receptor (1)

HER (1)

Hedgehog/Smoothened (1)

PD-1/PD-L1 (1)

Proton pump (1)

HCV Protease (1)

PDGFR (1)

PGE Synthase (1)

GSK-3 (1)

Phosphatase (1)

Phospholipase (1)

Glutathione reductase (1)

PKA (1)

GluR (1)

PKM (1)

Potassium Channel (1)

Glucosidase (1)

Glucagon Receptor (1)

Gamma-secretase (1)

FXR (1)

化合物ライブラリー情報実例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty