Reprogramming Compound Library

カタログ番号 L8110

ライブラリー構成化合物リスト Excel SDF

Cellular reprogramming refers to the process by which differentiated somatic cells are reversed to a pluripotent or totipotent state under certain conditions. Traditional reprogramming techniques have limitations in clinical applications due to problems such as the integration of exogenous genes, while the study of small molecule compounds to induce pluripotent stem cells has opened up a new approach to somatic cell reprogramming.

Small molecule compound-induced reprogramming has a lot of advantages. For instance, integration into the genome can be avoided, so as immunogenicity; the target can be acted upon directly through the cell membrane with simple manipulation; effects are reversible, multiple targets can be regulated at the same time, and cell fates are controlled precisely.

Small molecule compound-induced pluripotent stem cells have great potential in drug discovery, cell therapy, and disease modeling, opening up new avenues for the treatment of major diseases.

TargetMol’s Reprogramming Compound Library is a unique collection of 1840 bioactive small molecule compounds of cellular reprogramming-related signaling pathways, providing an effective tool for cellular reprogramming research.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。また、個人の方への販売は行っておりません。

パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

お問い合わせはこちら

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]

ライブラリ構成化合物リストを依頼する

製品概要

細胞のリプログラミングに関連する1840種類の生物活性低分子化合物を網羅した独自のコレクションであり、細胞のリプログラミング研究における効果的なツール
MEK、TGF-β、GSK3、wntなどのターゲットをカバー
化学構造的の多様性、薬理作用、細胞膜透過性をもつ化合物群
化合物の概要、化学構造、標的、活性、IC50値など、詳細な情報を提供
NMR と HPLC/LCMS により高純度と高品質を担保し、偽陽性率を低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
ブルーアイス同梱にて出荷

サポートファイル

ライブラリーの取扱説明書 (635 KB) TargetMol のライブラリーカタログ (13.2 MB) ExcelおよびSDFファイル形式でのライブラリー構成化合物リストの要求

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

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化合物ライブラリー情報実例

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