ホーム 計算ツール
代理店ログイン

Anti-Colorectal Cancer Compound Library

カタログ番号 L2194
  ライブラリー構成化合物リスト   Excel SDF

Colorectal Cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is one of the deadliest malignancies worldwide and a serious threat to human health. The morbidity rate and mortality rate of CRC are both rising in recent years, and the prevalence has increased with age. Generally, the aging of population and prevalent poor lifestyles are major contributing factors to CRC, and the lack of exercise, obesity, and smoking also contribute to a significantly increased risk of colorectal cancer.

The treatments for colorectal cancer include surgery, radiotherapy, chemotherapy and targeted therapy. Early stage cancer can be cured by surgery, while advanced metastatic cancer is usually treated with chemotherapy combined with targeted therapy. Studies have shown that dysregulation of several signaling pathways and targets are related to colorectal cancer, such as: VEGFR, EGFR, Wnt/β-catenin, p53, TGF-β, etc.

The TargetMol Anti-Colorectal Cancer Compound Library is a collection of 1545 compounds related to colorectal cancer, including compounds that have been reported to have therapeutic effects in colorectal cancer, as well as compounds targeting colorectal cancer-related targets, and is a good tool for anti-colorectal cancer drug development.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
Get quote

製品概要

  • 大腸がんに関連する1545種類の化合物からなるライブラリー
  • 大腸がんの治療効果が報告されている、もしくは大腸がんに関連するターゲットを持つ化合物を収集し、大腸がん治療薬の開発に向けたハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • 上市薬もしくは臨床試験段階の化合物を含む
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • NMRとHPLC/LCMSにより高純度と高品質を担保し、偽陽性を低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L2194)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Apoptosis (277)
Autophagy (210)
PI3K (162)
EGFR (149)
VEGFR (141)
COX (116)
mTOR (87)
Akt (87)
ERK (84)
p38 MAPK (83)
Wnt/beta-catenin (77)
Raf (69)
c-Met/HGFR (66)
AMPK (66)
NF-κB (64)
PDGFR (61)
Ras (58)
CDK (55)
GSK-3 (55)
STAT (52)
TGF-beta/Smad (51)
JNK (48)
c-Kit (45)
Antibacterial (43)
MEK (43)
MAPK (42)
Src (42)
FGFR (40)
Endogenous Metabolite (40)
FLT (39)
DNA-PK (37)
p53 (36)
S6 Kinase (31)
DNA/RNA Synthesis (29)
HER (29)
Parasite (24)
ALK (24)
ATM/ATR (22)
Reactive Oxygen Species (21)
c-RET (20)
PKC (20)
PDK (19)
Antibiotic (18)
Gamma-secretase (18)
Bcr-Abl (17)
Mdm2 (17)
Ferroptosis (17)
E1/E2/E3 Enzyme (17)
JAK (17)
Caspase (16)
Aurora Kinase (16)
Mitophagy (16)
PARP (15)
TNF (15)
Antifungal (15)
TAM Receptor (14)
PI4K (14)
PKA (13)
Casein Kinase (13)
IGF-1R (13)
Dehydrogenase (12)
Rho (12)
Influenza Virus (12)
PPAR (11)
P450 (11)
BCL (11)
Potassium Channel (11)
Trk receptor (11)
c-Fms (11)
FAK (10)
IL Receptor (10)
Tyrosine Kinases (10)
Sirtuin (10)
HIV Protease (10)
MMP (9)
Lipoxygenase (9)
Chk (9)
Topoisomerase (9)
ROCK (8)
HDAC (8)
Nucleoside Antimetabolite/Analog (8)
NOS (8)
Beta Amyloid (8)
Calcium Channel (8)
Phosphatase (8)
Sodium Channel (8)
ROS (7)
PDE (7)
HCV Protease (7)
HSV (7)
Prostaglandin Receptor (7)
PTEN (7)
Epigenetic Reader Domain (6)
Tyrosinase (6)
Phospholipase (5)
BTK (5)
TLR (5)
Antioxidant (5)
Estrogen/progestogen Receptor (5)
HSP (5)
Virus Protease (5)
ASK (5)
MNK (5)
Porcupine (5)
MLK (5)
MELK (5)
Tie-2 (5)
SGK (5)
IκB/IKK (5)
Carbonic Anhydrase (5)
Ephrin Receptor (5)
Aryl Hydrocarbon Receptor (5)
Antiviral (5)
Microtubule Associated (5)
SIK (5)
Interleukin (5)
Integrin (4)
HIF (4)
ATPase (4)
TOPK (4)
Hydroxylase (4)
Estrogen Receptor/ERR (4)
AChR (4)
NO Synthase (4)
Serine Protease (4)
PGE Synthase (4)
IAP (4)
HIF/HIF Prolyl-Hydroxylase (4)
ROS Kinase (4)
Drug Metabolite (4)
Glucosidase (4)
Adrenergic Receptor (4)
PLK (3)
AChE (3)
DNA Alkylator/Crosslinker (3)
GABA Receptor (3)
Antifection (3)
KLF (3)
Adenosine Receptor (3)
GTPase (3)
CSF-1R (3)
MRP (3)
DNA Alkylation (3)
Mitochondrial Metabolism (3)
P-gp (3)
Syk (3)
Glutathione Peroxidase (3)
HBV (2)
Transferase (2)
Nrf2 (2)
Kinesin (2)
RIP kinase (2)
NADPH (2)
Histamine Receptor (2)
BACE (2)
IRAK (2)
Hck (2)
Proton pump (2)
Pim (2)
IRE1 (2)
5-HT Receptor (2)
Gap Junction Protein (2)
Discoidin Domain Receptor (DDR) (2)
APC (2)
CaMK (2)
Chloride channel (2)
DYRK (2)
Beta-Secretase (2)
BMI-1 (2)
Fatty Acid Synthase (2)
SARS-CoV (2)
LRRK2 (2)
transporter (2)
TRP/TRPV Channel (2)
FAAH (2)
CCR (2)
Histone Methyltransferase (2)
Androgen Receptor (2)
DNA Methyltransferase (1)
Aromatase (1)
Cannabinoid Receptor (1)
DHFR (1)
PROTACs (1)
NADPH-oxidase (1)
Arginase (1)
GPR (1)
RSV (1)
GPX (1)
Reductase (1)
ROR (1)
PD-1/PD-L1 (1)
CRISPR/Cas9 (1)
Reverse Transcriptase (1)
Retinoid Receptor (1)
UGT (1)
Dopamine Receptor (1)
PAI-1 (1)
MTH1 (1)
cAMP (1)
GluR (1)
KSP (1)
Somatostatin (1)
Serine/threonin kinase (1)
Glucokinase (1)
PYK2 (1)
Opioid Receptor (1)
FLAP (1)
DUB (1)
Immunology/Inflammation related (1)
Neurotensin Receptor (1)
Leukotriene Receptor (1)
FXR (1)
Glucocorticoid Receptor (1)
Myosin (1)
NMDAR (1)
LDL (1)
DNA (1)
Antifolate (1)
hCE (1)
Histone Acetyltransferase (1)
AhR (1)
cholecystokinin (1)
RAAS (1)
DAPK (1)
Progesterone Receptor (1)
c-Myc (1)
Apelin receptor (1)
Methionine Adenosyltransferase (MAT) (1)
CD73 (1)
ATP Citrate Lyase (1)
NPC1L1 (1)
Wee1 (1)
Amino Acids and Derivatives (1)
Ligands for Target Protein for PROTAC (1)
YAP (1)
ACK (1)
PERK (1)
BCRP (1)
OCT (1)
S1P Receptor (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE