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Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library

カタログ番号 L6740
  ライブラリー構成化合物リスト   Excel SDF

Colorectal cancer (CRC) is one of the most common malignancies. Most cases of CRC are sporadic, and the global morbidity rate of CRC is rising due to prevalent poor dietary habits and lifestyles, including overconsumption of meat, alcohol, and lack of adequate physical exercise. Colorectal cancer is known with insidious onset and poor prognosis, thus there is a strong need for public health promotion, effective prevention and intervention strategies for it.

With the increasing research on the pathogenesis of colorectal cancer, the application of active ingredients of Chinese medicine in the prevention and treatment of CRC has been researched.

Chinese medicine can inhibit the occurrence and development of colorectal cancer by regulating multiple signaling pathways, participating in regulating the proliferation, differentiation and apoptosis of cancer cells, destroying the survival environment of cancer cells and enhancing the body's immune system.

The Targetmol Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library selected 382 Colorectal cancer-related TCM compounds, among which include TCM with tonic effects such as ginseng, astragalus, and TCM with heat-clearing and detoxifying effects such as scutellaria, rhubarb, etc. With more clear biological activity information, the library provides a powerful tool for anti-colon cancer related research.

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パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
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製品概要

  • 中医薬から382種の抗大腸癌効果を示す化合物を収集、薬剤開発や薬理学研究に有用なツール
  • フラボノイド、サポニン、テルペノイド、アルカロイドなど多様な分子構造
  • Wnt /β-catenin、TGF-beta / Smad、NF-κB、Notch等様々なターゲットをカバー
  • NMR と HPLC/LCMS により高純度と高品質を担保し、偽陽性率を低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L6740)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

NF-κB (160)
Apoptosis (97)
Autophagy (82)
Reactive Oxygen Species (79)
COX (52)
Endogenous Metabolite (50)
Antibacterial (38)
TNF (19)
ERK (18)
Antifungal (17)
p38 MAPK (16)
EGFR (15)
Influenza Virus (14)
Wnt/beta-catenin (14)
Antioxidant (14)
STAT (13)
HIV Protease (13)
Topoisomerase (13)
P450 (12)
Parasite (12)
IL Receptor (12)
JNK (12)
Akt (11)
TGF-beta/Smad (10)
Mitophagy (10)
ROS (10)
Caspase (10)
NO Synthase (10)
Lipoxygenase (9)
NOS (9)
Ferroptosis (9)
DNA/RNA Synthesis (8)
PPAR (7)
IκB/IKK (7)
VEGFR (7)
GABA Receptor (7)
HDAC (6)
Gamma-secretase (6)
Beta Amyloid (6)
TLR (6)
Prostaglandin Receptor (6)
MMP (6)
Calcium Channel (6)
p53 (6)
AMPK (5)
HIF/HIF Prolyl-Hydroxylase (5)
Antibiotic (5)
PI3K (5)
Nrf2 (5)
PKC (5)
5-HT Receptor (5)
JAK (4)
Tyrosinase (4)
ATPase (4)
AChR (4)
Mitochondrial Metabolism (4)
BCL (4)
CDK (4)
NOD (4)
Integrin (3)
SARS-CoV (3)
HSV (3)
Virus Protease (3)
TRP/TRPV Channel (3)
AChE (3)
PGE Synthase (3)
HER (3)
P-gp (3)
HIF (3)
MAO (3)
Sodium Channel (3)
IAP (3)
Phospholipase (3)
Dehydrogenase (3)
PARP (3)
Cannabinoid Receptor (3)
Opioid Receptor (3)
MEK (2)
NOD-like Receptor (NLR) (2)
Syk (2)
Anti-infection (2)
NADPH-oxidase (2)
Antiviral (2)
Potassium Channel (2)
Microtubule Associated (2)
IRAK (2)
Casein Kinase (2)
Trk receptor (2)
S6 Kinase (2)
Sirtuin (2)
Monoamine Oxidase (2)
Interleukin (2)
Hedgehog/Smoothened (2)
RANKL/RANK (2)
Estrogen Receptor/ERR (2)
PKA (2)
GSK-3 (2)
PDE (2)
RAAS (2)
c-Met/HGFR (2)
Estrogen/progestogen Receptor (2)
Glucosidase (2)
HCV Protease (2)
Antifection (2)
mTOR (2)
Chloride channel (2)
IGF-1R (2)
Epigenetic Reader Domain (2)
Carbonic Anhydrase (2)
Transferase (1)
NADPH (1)
FGFR (1)
PKM (1)
Histamine Receptor (1)
Platelet aggregation (1)
Proton pump (1)
Reductase (1)
BACE (1)
FAK (1)
PD-1/PD-L1 (1)
Arginase (1)
Ras (1)
CFTR (1)
Tyrosine Kinases (1)
Src (1)
ROS Kinase (1)
ROR (1)
DHFR (1)
HBV (1)
Adrenergic Receptor (1)
Liver X Receptor (1)
RSV (1)
CaMK (1)
MAPK (1)
Acyltransferase (1)
Mdm2 (1)
PTEN (1)
CCR (1)
HSP (1)
FAAH (1)
Fatty Acid Synthase (1)
Aminopeptidase (1)
Smo (1)
Histone Acetyltransferase (1)
transporter (1)
NMDAR (1)
Leukotriene Receptor (1)
Drug Metabolite (1)
ATM/ATR (1)
GST (1)
Raf (1)
Reverse Transcriptase (1)
LDL (1)
Retinoid Receptor (1)
Bcr-Abl (1)
UGT (1)
E1/E2/E3 Enzyme (1)
Immunology/Inflammation related (1)
Androgen Receptor (1)
Hydroxylase (1)
Proteasome (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE