Anti-Cancer Drug Library

カタログ番号 L2150

ライブラリー構成化合物リスト Excel SDF

過去数十年、がん研究と治療法の進歩により多くの画期的な発見や成功を実現しましたが、がんは人類の健康に対する重大な脅威であり、心身の苦痛・困難を負うリスクは依然として高いままです。がん細胞は、隣接細胞との接触阻止機構やプログラム細胞死といった正常な細胞シグナル応答を欠くため、分化することなく分裂し続け多くの損傷を引き起こし、新しい組織に浸潤します。またクロマチンに生じた変化は、異常に亢進した代謝の維持に必要な酸素や栄養素の安定供給を確保するための血管新生を誘導します。

本製品はFDA承認薬有効成分や臨床試験段階の化合物から抗がん活性物質2900種類を厳選したライブラリーです。腫瘍関連研究や抗腫瘍薬スクリーニングにご活用ください。

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。また、個人の方への販売は行っておりません。

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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]

ライブラリ構成化合物リストを依頼する

製品概要

ハイスループットスクリーニング(HTS)とハイコンテンツスクリーニング(HCS)に最適な、2900種の抗がん剤
非臨床試験および臨床試験で生物活性と安全性が確認済み
がん発生のメカニズム研究や抗腫瘍薬のドラッグリポジショニングのツールとして効果的
肺がん、乳がん、白血病、リンパ腫など15種類のがんに関与するPI3K、HDAC、mTOR、CDK、Aurora Kinase、JAKなどの主要なターゲットをカバー
化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
構造的多様性、薬効、細胞膜透過性を有する化合物
NMRとHPLC/LCMSにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
ブルーアイス同梱にて出荷

サポートファイル

ライブラリーの取扱説明書 (635 KB) TargetMol のライブラリーカタログ (13.2 MB) ExcelおよびSDFファイル形式でのライブラリー構成化合物リストの要求

ライブラリーの構成

Autophagy (442)

Apoptosis (411)

5-HT Receptor (195)

Endogenous Metabolite (183)

Adrenergic Receptor (178)

Antibacterial (147)

COX (135)

Antibiotic (120)

DNA/RNA Synthesis (119)

Dopamine Receptor (118)

Histamine Receptor (104)

Sodium Channel (95)

Calcium Channel (88)

Potassium Channel (88)

VEGFR (80)

EGFR (71)

Parasite (68)

AChR (66)

Reactive Oxygen Species (65)

PI3K (63)

Glucocorticoid Receptor (62)

P450 (59)

GABA Receptor (57)

FLT (55)

Topoisomerase (52)

PPAR (52)

PDGFR (51)

HIV Protease (51)

NF-κB (51)

CDK (50)

Ferroptosis (48)

JAK (47)

c-Kit (47)

FGFR (44)

HDAC (44)

Estrogen/progestogen Receptor (42)

Microtubule Associated (42)

Antifungal (41)

c-Met/HGFR (40)

Dehydrogenase (39)

Influenza Virus (38)

Mitophagy (38)

mTOR (38)

Estrogen Receptor/ERR (35)

Src (35)

Nucleoside Antimetabolite/Analog (34)

iGluR (32)

SARS-CoV (30)

Androgen Receptor (30)

Tyrosine Kinases (29)

Bcr-Abl (29)

Prostaglandin Receptor (28)

PDE (27)

Raf (27)

Serotonin Transporter (24)

Proton pump (23)

Akt (23)

Adenosine Receptor (23)

Norepinephrine (23)

ATPase (23)

DNA Alkylator/Crosslinker (22)

Virus Protease (22)

P-gp (21)

MEK (21)

TRP/TRPV Channel (21)

NMDAR (21)

TNF (21)

PARP (21)

HER (21)

HSV (20)

p38 MAPK (20)

HSP (19)

Aurora Kinase (19)

PKC (19)

ERK (18)

ALK (18)

Opioid Receptor (18)

Epigenetic Reader Domain (18)

ROS (18)

c-RET (18)

AMPK (17)

RAAS (17)

Trk receptor (17)

Phosphatase (16)

BCL (16)

HBV (16)

MMP (15)

HIF/HIF Prolyl-Hydroxylase (15)

GNRH Receptor (15)

TAM Receptor (15)

BTK (15)

Carbonic Anhydrase (15)

Retinoid Receptor (15)

Antifolate (14)

GSK-3 (14)

HCV Protease (14)

Drug Metabolite (14)

STAT (14)

E1/E2/E3 Enzyme (14)

Caspase (14)

DNA Alkylation (14)

Reverse Transcriptase (13)

c-Fms (13)

Mitochondrial Metabolism (13)

Histone Methyltransferase (13)

CXCR (13)

Progesterone Receptor (13)

MRP (12)

TGF-beta/Smad (12)

CFTR (12)

p53 (12)

HMG-CoA Reductase (12)

Lipoxygenase (12)

MAO (12)

DHFR (12)

IL Receptor (12)

Proteasome (12)

DNA-PK (12)

IGF-1R (11)

Transferase (11)

Chk (11)

GluR (11)

Gamma-secretase (11)

Interleukin (11)

FAK (11)

Nrf2 (10)

PKA (10)

HIF (10)

Wnt/beta-catenin (10)

Hedgehog/Smoothened (10)

Antioxidant (10)

CaMK (10)

SGLT (10)

Beta Amyloid (10)

Chloride channel (10)

ROCK (10)

CSF-1R (9)

Monoamine Oxidase (9)

DNA Methyltransferase (9)

Antifection (9)

P2X Receptor (9)

PLK (9)

GPR (9)

AChE (9)

TLR (9)

S1P Receptor (9)

ABC (8)

Sirtuin (8)

Indoleamine 2,3-Dioxygenase (IDO) (8)

Mdm2 (8)

Phospholipase (8)

S6 Kinase (8)

IAP (8)

Smo (8)

JNK (8)

Syk (8)

Neurokinin receptor (8)

DNA (7)

Sigma receptor (7)

Monoamine Transporter (7)

NADPH (7)

Thrombin (7)

LPL Receptor (7)

Guanylate cyclase (7)

P2Y Receptor (7)

ATM/ATR (7)

Endothelin Receptor (7)

Aromatase (7)

Histone Demethylase (7)

ROS Kinase (7)

Ras (7)

Integrin (7)

NO Synthase (6)

CCR (6)

RIP kinase (6)

Antiviral (6)

IκB/IKK (6)

ribosome (6)

Vasopressin Receptor (6)

PAK (6)

cholecystokinin (6)

Kinesin (6)

Isocitrate Dehydrogenase (IDH) (6)

Casein Kinase (6)

Fatty Acid Synthase (6)

Leukotriene Receptor (6)

Pim (5)

Hydroxylase (5)

Glutathione Peroxidase (5)

Tie-2 (5)

Serine Protease (5)

Ephrin Receptor (5)

LTR (5)

IFNAR (5)

FXR (5)

CaSR (5)

NOD (5)

DPP-4 (5)

PGE Synthase (5)

GPCR19 (4)

Oxytocin Receptor (4)

Xanthine Oxidase (4)

Serine/threonin kinase (4)

Melatonin Receptor (4)

Aryl Hydrocarbon Receptor (4)

KSP (4)

Aminopeptidase (4)

Amino Acids and Derivatives (4)

AhR (4)

IDO (4)

Annexin A (4)

Tyrosinase (4)

Rho (3)

OX Receptor (3)

Wee1 (3)

UGT (3)

RSV (3)

PDK (3)

Somatostatin (3)

ROR (3)

STING (3)

Reductase (3)

IRAK (3)

OAT (3)

Cannabinoid Receptor (3)

Hexokinase (3)

Liver X Receptor (3)

Free radical scavengers (3)

DNA gyrase (3)

Melanocortin Receptor (3)

Cysteine Protease (3)

CRM1 (3)

Monocarboxylate transporter (3)

MT Receptor (3)

Na-K-Cl cotransporter (3)

Adenosine deaminase (3)

NAMPT (3)

NOD-like Receptor (NLR) (3)

Beta-Secretase (2)

VDA (2)

Histone Acetyltransferase (2)

Acyltransferase (2)

GST (2)

Glutathione reductase (2)

Glucosidase (2)

GHSR (2)

Gap Junction Protein (2)

DUB (2)

Discoidin Domain Receptor (DDR) (2)

Arginase (2)

TOPK (2)

Decarboxylase (2)

ATP Citrate Lyase (2)

Imidazoline Receptor (2)

c-Myc (2)

Cell wall (2)

Telomerase (2)

CD73 (2)

CAT (2)

BCRP (2)

PYK2 (2)

YAP (2)

p97 (2)

LDL (2)

Porcupine (2)

NEDD8 (2)

Lipid (2)

MAPK (2)

PD-1/PD-L1 (2)

NOS (2)

Protease-activated Receptor (2)

IRE1 (2)

Myosin (1)

Na+/Ca2+ Exchanger (1)

Thioredoxin (1)

N-Acetylglucosaminyltransferase (1)

Thrombopoietin Receptor (1)

PAI-1 (1)

cAMP (1)

Bradykinin Receptor (1)

PAFR (1)

BMI-1 (1)

Immunology/Inflammation related (1)

PAD (1)

transporter (1)

Survivin (1)

BACE (1)

NADPH-oxidase (1)

ASK (1)

Aquaporin (1)

Neprilysin (1)

VDAC (1)

Anion Exchanger (1)

advanced glycation end products (1)

OXPHOS (1)

ACK (1)

CGRP Receptor (1)

CRFR (1)

MTH1 (1)

Glucokinase (1)

Pyroptosis (1)

Hydrogenase (1)

KLF (1)

RAR/RXR (1)

HCN Channel (1)

Hck (1)

GTPase (1)

LHRH (1)

GRK (1)

NPC1L1 (1)

Glutaminase (1)

Lipase (1)

Glucagon Receptor (1)

Stemness kinase (1)

Platelet aggregation (1)

Galectin (1)

MALT (1)

Factor Xa (1)

FAAH (1)

DYRK (1)

SGK (1)

PI4K (1)

MELK (1)

MLK (1)

MNK (1)

PERK (1)

Complement System (1)

GlyT (1)

化合物ライブラリー情報実例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty