ホーム 計算ツール
代理店ログイン

Anti-Fibrosis Compound Library

カタログ番号 L9810
  ライブラリー構成化合物リスト   Excel SDF

Fibrosis, also known as fibrotic scarring, is a pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodeling and the formation of permanent scar tissue. If highly progressive, the fibrotic process eventually leads to organ malfunction and death. Fibrosis affects nearly every tissue in the body, such as lung, liver, kidney, bone marrow, etc. Fibrosis is the final, common pathological outcome of many chronic inflammatory diseases, including scleroderma, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, myelofibrosis and systemic lupus erythematosus.

TargetMol’s Anti-Fibrosis Compound Library collects 1180 potential anti-fibrosis compounds, including inhibitors to TGF-beta, TNF-alpha, MMP, etc., antioxidants, anti-inflammatory compounds, etc. It is a powerful tool for research in fibrosis and related drug development.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
Get quote

製品概要

  • 抗線維化効果が期待される1180化合物からなるHTSおよびHCSに最適な当社独自のコレクション
  • ターゲットには、TGFβ、TNFα、MMP、EGFR、NADPH-oxidaseなどをカバー
  • 一部に上市薬を含む
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • NMRおよびHPLC/LCMS により高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L9810)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Apoptosis (199)
Autophagy (154)
Reactive Oxygen Species (129)
Endogenous Metabolite (114)
COX (112)
VEGFR (91)
Antibacterial (89)
MMP (78)
Antioxidant (77)
NF-κB (74)
TNF (69)
TGF-beta/Smad (63)
FGFR (57)
PDGFR (56)
Wnt/beta-catenin (41)
ROS (39)
c-Kit (34)
IL Receptor (34)
FLT (32)
Parasite (30)
Antifungal (30)
Influenza Virus (27)
ALK (26)
EGFR (25)
JAK (22)
Antibiotic (22)
Glucocorticoid Receptor (22)
STAT (22)
Ferroptosis (21)
NADPH (21)
ERK (20)
p38 MAPK (20)
P450 (19)
NO Synthase (19)
HIV Protease (19)
Src (19)
Cannabinoid Receptor (18)
PPAR (17)
c-Met/HGFR (17)
CFTR (16)
Nrf2 (15)
Mitophagy (15)
Virus Protease (15)
Caspase (13)
DNA/RNA Synthesis (13)
c-RET (12)
Interleukin (12)
Bcr-Abl (12)
NOS (12)
AMPK (12)
PARP (11)
PDE (11)
Calcium Channel (11)
Akt (11)
Lipoxygenase (11)
BCL (10)
PKC (10)
PI3K (10)
Tyrosinase (10)
Prostaglandin Receptor (10)
Anti-infection (10)
CDK (9)
JNK (9)
Aurora Kinase (9)
Mitochondrial Metabolism (9)
Tyrosine Kinases (9)
Trk receptor (8)
GABA Receptor (8)
Raf (8)
HIF/HIF Prolyl-Hydroxylase (8)
TLR (8)
Estrogen/progestogen Receptor (8)
ROS Kinase (8)
Dehydrogenase (7)
IκB/IKK (7)
Topoisomerase (7)
SARS-CoV (7)
Potassium Channel (7)
Phospholipase (6)
c-Fms (6)
Adrenergic Receptor (6)
P-gp (6)
Beta Amyloid (6)
TRP/TRPV Channel (6)
NADPH-oxidase (6)
NOD-like Receptor (NLR) (6)
HER (6)
AChE (6)
HSV (6)
Xanthine Oxidase (6)
LPA Receptor (6)
LPL Receptor (5)
ATPase (5)
S6 Kinase (5)
TAM Receptor (5)
CCR (5)
Adenosine Receptor (5)
Sodium Channel (5)
PKA (5)
5-HT Receptor (5)
Immunology/Inflammation related (5)
Estrogen Receptor/ERR (5)
CSF-1R (5)
Syk (5)
Antiviral (5)
Glutathione Peroxidase (5)
Chloride channel (4)
PGE Synthase (4)
Reductase (4)
AChR (4)
MAPK (4)
GSK-3 (4)
Cysteine Protease (4)
NOD (4)
MEK (4)
Drug Metabolite (4)
Epigenetic Reader Domain (4)
Free radical scavengers (4)
HIF (4)
Histamine Receptor (4)
Chk (4)
HDAC (4)
Sirtuin (3)
mTOR (3)
Ephrin Receptor (3)
HSP (3)
Glucosidase (3)
Ligand for E3 Ligase (3)
Monoamine Oxidase (3)
UGT (3)
PDK (3)
ribosome (3)
Annexin A (3)
Phosphatase (3)
HCV Protease (3)
RAAS (3)
Retinoid Receptor (3)
Serine/threonin kinase (3)
Molecular Glues (3)
Reverse Transcriptase (3)
FAAH (3)
Casein Kinase (3)
Serine Protease (3)
GPR (3)
MLK (2)
FAK (2)
Microtubule Associated (2)
Porcupine (2)
Aromatase (2)
Histone Acetyltransferase (2)
Gap Junction Protein (2)
p53 (2)
Aminopeptidase (2)
RSV (2)
PAI-1 (2)
Discoidin Domain Receptor (DDR) (2)
Proteasome (2)
IAP (2)
Lipase (2)
Hedgehog/Smoothened (2)
Smo (2)
Opioid Receptor (2)
Antifection (2)
DNA gyrase (2)
P2X Receptor (2)
Tie-2 (2)
LTR (2)
Gamma-secretase (2)
RIP kinase (2)
IRE1 (2)
MAO (2)
MRP (2)
HBV (2)
BACE (2)
Leukotriene Receptor (2)
CXCR (2)
Integrin (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
PTEN (2)
Histone Methyltransferase (2)
IGF-1R (2)
Epoxide Hydrolase (2)
ROR (2)
Dynamin (1)
Galectin (1)
Hck (1)
Rho (1)
Proton pump (1)
Carbonic Anhydrase (1)
Transferase (1)
N-Acetylglucosaminyltransferase (1)
Platelet aggregation (1)
CaSR (1)
Monocarboxylate transporter (1)
c-Myc (1)
Hydrogenase (1)
Ras (1)
Melatonin Receptor (1)
Thrombin (1)
Progesterone Receptor (1)
Amino Acids and Derivatives (1)
IFNAR (1)
MyD88 (1)
HMG-CoA Reductase (1)
DNA Methyltransferase (1)
cell cycle arrest (1)
IRAK (1)
RAR/RXR  (1)
Survivin (1)
Liver X Receptor (1)
PAD (1)
advanced glycation end products (1)
Pyroptosis (1)
hCE (1)
ASK (1)
Somatostatin (1)
transporter (1)
CaMK (1)
ATM/ATR (1)
DNA (1)
Androgen Receptor (1)
Telomerase (1)
SGLT (1)
ATP Citrate Lyase (1)
OXPHOS (1)
PAK (1)
GST (1)
RANKL/RANK (1)
FLAP (1)
ROCK (1)
Amylase (1)
PLK (1)
Hydroxylase (1)
Glutathione reductase (1)
iGluR (1)
E1/E2/E3 Enzyme (1)
Guanylate cyclase (1)
Adiponectin receptor (1)
LDL (1)
AAK1 (AP2 associated kinase 1) (1)
Phosphorylase (1)
BTK (1)
Anion Exchanger (1)
PKM (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE