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Anti-Fungal Compound Library

カタログ番号 L4500
  ライブラリー構成化合物リスト   Excel SDF

Invasive fungal infections are a significant health problem in immunocompromised patients. However, the number of therapeutic options for the treatment of invasive fungal infections is quite limited, and include only three structural classes of drugs: polyenes, azoles, and echinocandins. Anti-fungi compound library from TargetMol is a unique collection of 252 compounds that include natural product (polyene and echinocandins), target specific chemicals (azoles) and FDA approved antifungal agents.More recently, interest in natural product-based screening has enjoyed a renaissance. This has been driven not only by the recognition of the valuable features of natural product hits and that natural substances have evolved over a very long selection process to form optimal interactions with biological macromolecules, but by improvements in structure-identification, separation, and target identification. Recently, broad interest in combination screening to identify molecules that synergize with existing classes of antibacterial and antifungal drugs as an approach to improve efficacy has emerged. Our anti-fungi compound library is an effective tool for drug repurposing screening and combination screening.

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パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • 252種の抗真菌化合物を収集した独自の化合物ライブラリー
  • ドラッグリポジショニング、薬剤併用スクリーニングなどの生物学的研究に最適
  • 体部白癬やカンジダ症に対する抗真菌剤、および真菌特異的ターゲットの阻害剤などを収集
  • 臨床試験において生物活性と安全性が確認済みであり一部はFDA承認済み
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • 構造的多様性、薬効、細胞膜透過性を有する化合物
  • NMRとHPLC/LCMSにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L4500)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Antifungal (220)
Antibacterial (84)
Antibiotic (68)
Apoptosis (27)
Endogenous Metabolite (23)
Parasite (16)
Autophagy (15)
P450 (11)
Antifection (10)
Anti-infection (10)
Influenza Virus (9)
Reactive Oxygen Species (9)
DNA/RNA Synthesis (6)
NF-κB (5)
PKC (4)
Virus Protease (4)
COX (4)
ATPase (4)
Ferroptosis (4)
Antioxidant (3)
HSV (3)
Potassium Channel (3)
p38 MAPK (3)
MAO (3)
Phosphatase (3)
Hedgehog/Smoothened (3)
MMP (2)
TNF (2)
AChE (2)
PPAR (2)
IL Receptor (2)
Mitochondrial Metabolism (2)
Topoisomerase (2)
Microtubule Associated (2)
Estrogen/progestogen Receptor (2)
NADPH (2)
Sodium Channel (2)
PKA (2)
Mitophagy (2)
Dehydrogenase (2)
Tyrosinase (2)
Dopamine Receptor (2)
Ras (1)
p53 (1)
IκB/IKK (1)
ribosome (1)
NOD (1)
5-HT Receptor (1)
NADPH-oxidase (1)
Hydroxylase (1)
AhR (1)
AChR (1)
Nrf2 (1)
RSV (1)
Reverse Transcriptase (1)
STAT (1)
Phospholipase (1)
HIV Protease (1)
mTOR (1)
HBV (1)
Src (1)
CRM1 (1)
Histamine Receptor (1)
JNK (1)
Proton pump (1)
Integrin (1)
Wnt/beta-catenin (1)
VEGFR (1)
Caspase (1)
IRE1 (1)
UGT (1)
NMDAR (1)
ERK (1)
FAAH (1)
Aryl Hydrocarbon Receptor (1)
E1/E2/E3 Enzyme (1)
Gamma-secretase (1)
ROS (1)
Opioid Receptor (1)
NOS (1)
Lipoxygenase (1)
CaMK (1)
DNA (1)
Interleukin (1)
HSP (1)
Sirtuin (1)
JAK (1)
Monoamine Oxidase (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE