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Bioactive Compound Library

カタログ番号 L4000
  ライブラリー構成化合物リスト   Excel SDF

It contains more than 14439 small molecule compounds, with known biological activities causing biological reaction in cells, tissue even whole body, including Clinical compound library (L3400), Preclinical compound library (L3410), and Approved drug library (L1000). All compounds have clear targets and detailed information description, which is the key point to drug research and development like drug repurposing, small molecule inducing stem cell differentiation, and target identification in mechanism interrogation.

Many scientists have identified small molecules that can regulate cell fate and function, and stem cell differentiation by screening annotated bioactive compound library with confirmed activity and known targets. Recent advances in iPSC technology have made reprogramming of somatic cells towards pluripotency possible and simpler. Using both phenotypic screening and hypothesis-driven approaches, a growing number of compounds have been identified that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules with success in cardiomyocyte differentiation and proliferation, neural progenitor cells, etc.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • 全て生物活性が確認済みである14439化合物のコレクションで、ハイスループットスクリーニング (HTS) 、ハイコンテンツスクリーニング (HCS) 、細胞分化、ターゲット同定に最適
  • 全化合物のターゲットが明確
  • ドラッグリポジショニングや細胞誘導におけるターゲットスクリーニングのツールとして有効
  • がん、代謝、免疫系、心血管系など、多岐にわたる疾患研究領域をカバー
  • 詳細な手順書、化合物構造、ターゲット情報、活性の説明を添付
  • 化学構造的の多様性、薬理作用、細胞膜透過性をもつ化合物群
  • NMR と HPLC/LCMS により高純度と高品質を担保し、偽陽性率を低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L4000)

Publications Cited TargetMol Libraries

1. ACS nano. 2023. 2. Advanced Science. 2022: 2203388.. 3. Advanced Science. 2020, 7(16): 2000925. 4. Angewandte Chemie. 2021. 5. Signal transduction and targeted therapy. 2021, 6(1): 1-4. 6. Autophagy. 2023: 1-20. 7. Angewandte Chemie International Edition. 2020, 59(24): 9601-9609. 8. The EMBO Journal. 2021, 40(16): e107403. 9. Journal of Cell Biology. 2022, 221(5): e202112024.
10. Cell Reports. 2022, 39(2): 110622. 12. Journal of Translational Medicine. 2023, 21(1): 1-20.. 13. Acta Pharmaceutica Sinica B. 2021 Jun;11(6):1555-1567. 14. Frontiers in Molecular Biosciences. 2022, 9. 15. Marine Drugs. 2023, 21(4): 218. 16. Pharmaceuticals. 2022, 15(5): 556. 17. Frontiers in chemistry. 2022, 10. 18. Journal of Enzyme Inhibition and Medicinal Chemistry. 2022, 37(1): 109-117.. 19. Methods. 2022, 205: 247-262. 20. ACS Infectious Diseases. 2021 Aug 13;7(8):2337-2351. 21. European Journal of Pharmaceutical Sciences. 2023: 106672.. 22. Cancer Science. 2021, 112(11): 4722. 23. Cognitive computation. 2021 Feb 2;1-13. 24. Neoplasia. 2020, 22(4): 179-191. 25. Investigational New Drugs. 2019 May 14: 1-10. 26. Acta Biochimica et Biophysica Sinica. 2021. 27. Interdisciplinary Sciences, Computational Life Sciences. 2020, 12: 368-376. 28. SSRN. 2023. 29. Journal of Southern Medical University. 2022, 42(4): 554-560. 30. bioRxiv. 2022. 31. Journal of Southern Medical University. 2021, 41(12): 1835-1842. 32. bioRxiv. 2021 Feb 15;2021.02.13.431008. 33. Cell Stem Cell. 2022 Apr 29(4) 545–558. 34. Science Bulletin. 2022. 35. Science Translational Medicine. 2022, 14(656): eabn3231. 36. Science Advances. 2023, 9(9): eade3760. 37. Nature. 2020, 582: 289-293. 38. Nature Biotechnology. 2021, 39(11): 1444-1452. 39. Nature Communications. 2022, 13(1): 1-15.. 40. Nature Communications. 2023, 14(1): 1020.. 41. Nature Communications. 2023, 14(1): 2756.. 42. Blood. 2021, 137(11): 1478-1490. 43. Nucleic Acids Research. 2021. 44. Nature Communications. 2023, 14(1): 7574. 45. Acta Pharmaceutica Sinica B. 2022. 46. Protein & Cell. 2021, 12(11): 877-888. 47. Bone Research. 2023, 11(1): 54. 48. Pharmacology & Therapeutics. (2021): 107930. 49. Nature Communications. 2021, 12(1): 1-12. 50. Duo L, Chen Y, Liu Q, et al.Discovery of Novel SOS1 Inhibitors Using Machine Learning.RSC Medicinal Chemistry.2024 51. Wilson D M, Driedger D J, Liu D Y, et al.Targeted sampling of natural product space to identify bioactive natural product-like polyketide macrolides.Nature Communications.2024, 15(1): 2534. 52. Lv S, Pan Q, Lu W, et al.Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells.Scientific Reports.2024, 14(1): 7654. 53. Ma Y, Song Y, Wang J, et al.Discovery of novel covalent inhibitors of DJ-1 through hybrid virtual screening.Future Medicinal Chemistry.2024 (0).
隠し

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化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE