ホーム 計算ツール
代理店ログイン

Calcium Channel Compound Library

カタログ番号 L7200
  ライブラリー構成化合物リスト   Excel SDF

A calcium channel is an ion channel(plasma membrane protein) which shows selective permeability to calcium ions. Calcium channels constitute a large family of voltage- and ligand-operated ion channels. Calcium channels are ubiquitous, they can be found in almost any type of excitable (e.g., muscle, glial cells, neurons, etc.) and most unexcitable cells in a wide variety of species. Functions mediated by calcium channels include contraction of muscle, release of neurotransmitters and hormones by neurons and neuroendocrine cells, and control of gene transcription. They are targets for modulation by many intracellular signaling pathways including G proteins and phosphorylation. Calcium channels play pivotal roles in many human diseases, particularly of the cardiac and nervous systems, including pain, seizure, hypertension and migraine. Pharmacological blockers for some types of calcium channels are known, including clinically used drugs for hypertension and pain. In some cases such calcium channel blockers are highly selective for specific types of calcium channels, but there is great potential for developing more selective and more potent drugs targeting calcium channels.

TargetMol’s Calcium Channel Library collects the reported calcium channel blockers and agonists, and is an ideal tool for screening more selective and potent drugs targeting calcium channels.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
Get quote

製品概要

  • カルシウムチャネル機能を阻害もしくは促進する140種類の化合物を独自に収集したライブラリーで、ハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • ターゲットにはL型、T型、N型、受容体作動性カルシウムチャネルなどの各サブタイプ
  • 非臨床試験および臨床試験において生物活性と安全性が確認済みで、一部に承認薬を含む
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • 構造的多様性、薬効、細胞膜透過性を有する化合物
  • NMRとHPLCにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L7200)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Calcium Channel (140)
Autophagy (13)
Sodium Channel (12)
Potassium Channel (10)
Endogenous Metabolite (9)
AChR (8)
Apoptosis (6)
Adrenergic Receptor (5)
NF-κB (5)
TRP/TRPV Channel (4)
Parasite (4)
Reactive Oxygen Species (4)
GABA Receptor (4)
P450 (3)
COX (3)
Dopamine Receptor (3)
Histamine Receptor (3)
PKC (3)
PKA (2)
AMPK (2)
CaMK (2)
iGluR (2)
HIV Protease (2)
P-gp (2)
Carbonic Anhydrase (2)
DNA/RNA Synthesis (1)
EGFR (1)
TGF-beta/Smad (1)
SARS-CoV (1)
Chloride channel (1)
Antibacterial (1)
Prostaglandin Receptor (1)
Influenza Virus (1)
GST (1)
5-HT Receptor (1)
Antibiotic (1)
AhR (1)
Anti-infection (1)
Interleukin (1)
P2X Receptor (1)
GluR (1)
Serine/threonin kinase (1)
Src (1)
Reductase (1)
RAAS (1)
Phosphatase (1)
GSK-3 (1)
ATPase (1)
p38 MAPK (1)
Antioxidant (1)
Na+/Ca2+ Exchanger (1)
Virus Protease (1)
Wnt/beta-catenin (1)
ROCK (1)
cAMP (1)
Glucocorticoid Receptor (1)
PDE (1)
LDL (1)
PPAR (1)
ERK (1)
PAFR (1)
CDK (1)
Drug Metabolite (1)
Monoamine Transporter (1)
ROS (1)
Opioid Receptor (1)
IL Receptor (1)
DNA Methyltransferase (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE