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FDA-Approved Drug Library

カタログ番号 L4200
  ライブラリー構成化合物リスト   Excel SDF

All compounds in FDA approved drug library have well-characterized biological activity, clear targets, safety, and bioavailability – properties which could dramatically accelerate drug development and optimization. It is an effective and ideal tool for drug repurposing and cell differentiation induction. Detailed information on each compound in this library can help scientists quickly finish drug screening or make quick judgement on cell differentiation mechanism, and create conditions for further investigation on the mechanism of action.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • 1729 種類の FDA 承認済み医薬品の化合物を独自にコレクション
  • ハイスループットスクリーニング (HTS) とハイコンテンツスクリーニング (HCS) に最適
  • 非臨床試験および臨床試験でのエビデンスにより、生物活性と安全性が確認済み
  • 新旧の薬剤を用いた新しい薬剤の発見やターゲットの新規同定に有効なツール
  • 癌、心臓病、抗炎症、免疫学、神経精神疾患、鎮痛など、様々な研究分野をカバー
  • 化学構造的の多様性、薬理作用、細胞膜透過性をもつ化合物群
  • 化合物の概要、化学構造、標的、活性、IC50値など、詳細な情報を提供
  • NMR と HPLC/LCMS により高純度と高品質を担保し、偽陽性率を低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L4200)

Publications Cited TargetMol Libraries

1. Nature Biotechnology. 2021, 39(11): 1444-1452. 2. ACS Central Science. 2023. 3. Nature Communications. 2023, 14(1): 2756.. 4. Nature Communications. 2023, 14(1): 1020.. 5. Blood. 2021, 137(11): 1478-1490. 6. Advanced Science. 2021: 2101957. 7. Protein & Cell. 2021: 1-19.. 8. Bone Research. 2023, 11(1): 54. 9. Journal of Experimental & Clinical Cancer Research. 2023, 42(1): 1-27..
10. Pharmacology & Therapeutics. (2021): 107930. 11. Microbial Biotechnology. 2022, 15(2): 482-498. 12. Journal of Translational Medicine. 2022, 20(1): 1-11.. 13. Cancer Research. 2020. 14. Neuropsychopharmacology. 2022: 1-9. 15. Theranostics. 2020, 10(13): 5749-5762. 16. PLoS Biology. 2021, 19(10): e3001425. 17. Journal of Medicinal Chemistry. 2023. 18. Immunology. 2023;1–10.. 19. Microbiology Spectrum. 2022: e00884-22. 20. Elife. 2021, 10: e65962. 21. Translational Research. 2022. 22. European Journal of Medicinal Chemistry. 2023: 116018.. 23. International Journal of Molecular Sciences. 2022, 23(19): 11250. 24. Fundamental Research. 2023. 25. Cell Death & Disease. 2020, 11(3): 1-12. 26. International Journal of Molecular Sciences. 2022, 23(7): 4050. 27. International Journal of Molecular Sciences. 2020. 28. Viruses. 2021 Jun 3;13(6):1061. 29. International Journal of Oncology. 2022, 60(6): 1-13. 30. Journal of Molecular Cell Biology. 2023: mjad056. 31. Journal of Virus Eradication. 2023: 100327.. 32. Frontiers in Immunology. 2020, 11. 33. Scientific Reports. 2022 Nov 2;12(1):18506. 34. Molecules. 2022, 27(15): 5000.. 35. Antimicrobial agents and chemotherapy. 2021, 65(4): e02577-20. 36. Antimicrobial Agents and Chemotherapy. 2020, 64(9). 37. CNS Oncology. 2020. 38. Viruses. 2023, 15(8): 1666.. 39. ACS Infectious Diseases. 2021 Aug 13;7(8):2337-2351. 40. Journal of virology. 2018, 92(20): e01018-18.. 41. Virologica Sinica. 2022. 42. Journal of Proteome Research. 2020. 43. Journal of Biological Chemistry. 2016 Apr;291(17): 9218-9232.. 44. Acta Pharmacologica Sinica, 2019, 40(12): 1568-1577. 45. Neoplasia. 2020, 22(4): 179-191. 46. Virology. 2022. 47. Molecular Informatics. 2022. 48. Journal of Biomolecular Structure and Dynamics. 2020: 1-16. 49. Journal of Clinical Medicine. 2020, 9(5): 1473. 50. RSC Advances. 2021, 11(4): 2158-2166. 51. Orthopaedic Surgery. 2023. 52. Interdisciplinary Sciences: Computational Life Sciences, 2020, 12: 368-376. 53. Hollis R L, Elliott R, Dawson J C, et al.High throughput screening identifies dasatinib as synergistic with trametinib in low grade serous ovarian carcinoma.Gynecologic Oncology.2024, 186: 42-52. 54. Dou X, Huo T, Liu Y, et al.Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation.European Journal of Medicinal Chemistry.2024: 116323. 55. bioRxiv. 2023: 2023.05. 24.542186.. 56. SSRN. 2023. 57. bioRxiv. 2021. 58. AIP Publishing LLC. 2021, 2370(1): 070005. 59. researchsquare. 2022. 60. Chemrxiv. 2020. 61. Cell Stem Cell. 2022 Apr 29(4) 545–558. 62. Science Bulletin. 2022. 63. Science Translational Medicine. 2022, 14(656): eabn3231. 64. Science Advances. 2023, 9(9): eade3760. 65. Nature. 2020, 582: 289-293. 66. Nature Communications. 2022, 13(1): 1-15.. 67. Nucleic Acids Research. 2021. 68. Nature Communications. 2023, 14(1): 7574. 69. Advanced Science. 2020, 7(16): 2000925. 70. Angewandte Chemie. 2021. 71. Acta Pharmaceutica Sinica B. 2022. 72. Protein & Cell. 2021, 12(11): 877-888. 73. Nature Communications. 2021, 12(1): 1-12. 74. Journal of Cell Biology. 2022, 221(5): e202112024. 75. Liu T, Yue X, Chen X, et al.Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma.Cellular Oncology.2024: 1-18. 76. Fang Z Y, Zhang Z Y, Zheng Y D, et al.Repurposing cinacalcet suppresses multidrug-resistant Staphylococcus aureus by disruption of cell membrane and inhibits biofilm by targeting IcaR.Journal of Antimicrobial Chemotherapy.2024: dkae051. 77. Cao Z, Hou Y, Zhao Z, et al.Reactivating Hippo by Drug Compounds to Suppress Gastric Cancer and Enhance Chemotherapy Sensitivity.Journal of Biological Chemistry.2024: 107311. 78. Tao X, Cheng M, Huang X, et al.Dabrafenib Alleviates Hepatotoxicity Caused by Lenvatinib via Inhibiting the Death Receptor Signaling Pathway.Toxicology Letters.2024
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化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE