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Gut Microbial Metabolite Library

カタログ番号 L2540
  ライブラリー構成化合物リスト   Excel SDF

The gut microbiome in humans can be considered as an organ, which has functions critical for human metabolism, digestion, maintenance of gut barrier function and immunomodulation. Human metabolism is highly associated with altered microbiota composition.

Moreover, the gut microbiome has been linked to many diseases not classically associated with microbes, such as metabolic diseases including obesity and obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes mellitus (T2DM), rheumatoid arthritis and psychiatric disorders. The gastrointestinal (GI) tract is considered the largest immunological organ in the body having a central role in regulating immune homeostasis, relying on the dynamic interactions between intestinal epithelial cells, immune cells and microbiome in shaping specific immune responses to antigens. The gut microbiota contributes to host physiology through the production of a myriad of metabolites. These metabolites exert their effects within the host as signaling molecules (“messengers”) and substrates for metabolic reactions, such as influencing human energetics, suppressing inflammation through distinct mechanisms, regulating intestinal epithelial cell homeostasis, immune cell response, and neuronal excitability, etc. Therefore, the study on gut microbial metabolite will be helpful in discovering the mechanisms of some diseases and developing appropriate and effective therapies.

TargetMol’s Gut Microbial metabolite Library collects 614 gut microbial metabolites which can be used in research of gut microbiome and its related drug development.

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パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • 腸内細菌叢の代謝産物から614種類の生物活性化合物を独自に収集したライブラリーで、ハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • 探査および中鎖脂肪酸、アミノ酸、ビタミン、サッカライド、脂質などを含む
  • 腸内細菌叢の代謝および関連する創薬に最適
  • 化合物の概要、化学構造、標的、生物活性、IC50など詳細な情報を提供
  • NMRとHPLC/LCMSなどの品質管理により適正な構造と高純度を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L2540)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Endogenous Metabolite (506)
Apoptosis (36)
Autophagy (27)
Antibacterial (26)
Antioxidant (12)
Influenza Virus (11)
Antifungal (9)
Amino Acids and Derivatives (9)
Reactive Oxygen Species (9)
PPAR (8)
DNA/RNA Synthesis (7)
Ferroptosis (7)
Antibiotic (7)
5-HT Receptor (6)
NF-κB (6)
Calcium Channel (5)
iGluR (5)
Caspase (5)
Nrf2 (5)
Dehydrogenase (5)
Adenosine Receptor (4)
Virus Protease (4)
TRP/TRPV Channel (4)
FXR (4)
Nucleoside Antimetabolite/Analog (4)
Parasite (4)
Tyrosinase (4)
NO Synthase (4)
Mitophagy (4)
TNF (4)
COX (4)
P450 (4)
GPCR19 (4)
NMDAR (3)
PDE (3)
AhR (3)
Akt (3)
ERK (3)
GABA Receptor (3)
AMPK (3)
Chloride channel (3)
HIV Protease (3)
PI3K (3)
Phosphatase (3)
Histamine Receptor (3)
p38 MAPK (3)
FGFR (2)
Arginase (2)
ROS (2)
Mitochondrial Metabolism (2)
TGF-beta/Smad (2)
HDAC (2)
MMP (2)
Transferase (2)
Estrogen/progestogen Receptor (2)
GluR (2)
Epigenetic Reader Domain (2)
Histone Acetyltransferase (2)
Imidazoline Receptor (2)
Aryl Hydrocarbon Receptor (2)
Adrenergic Receptor (2)
PARP (2)
Potassium Channel (2)
GPR (1)
ROR (1)
Beta Amyloid (1)
P2Y Receptor (1)
Reductase (1)
Decarboxylase (1)
Dopamine Receptor (1)
Glucokinase (1)
PLK (1)
HIF (1)
DHFR (1)
aconitase (1)
Monocarboxylate transporter (1)
Cannabinoid Receptor (1)
AChR (1)
Neurokinin receptor (1)
Anti-infection (1)
NOD (1)
Carbonic Anhydrase (1)
HIF/HIF Prolyl-Hydroxylase (1)
NOD-like Receptor (NLR) (1)
ATPase (1)
CFTR (1)
Sirtuin (1)
P-gp (1)
Trk receptor (1)
IL Receptor (1)
MAO (1)
Wnt/beta-catenin (1)
Glucocorticoid Receptor (1)
Estrogen Receptor/ERR (1)
LDL (1)
Drug Metabolite (1)
MT Receptor (1)
Phosphorylase (1)
HBV (1)
GlyT (1)
Antifection (1)
Melatonin Receptor (1)
Fatty Acid Synthase (1)
HSV (1)
Lipoxygenase (1)
Prostaglandin Receptor (1)
MAPK (1)
HSP (1)
Antiviral (1)
Histone Demethylase (1)
PKC (1)
Acyltransferase (1)
AChE (1)
Lipase (1)
IGF-1R (1)
ATP Citrate Lyase (1)
EGFR (1)
JNK (1)
mTOR (1)
Glutathione Peroxidase (1)
CaMK (1)
Opioid Receptor (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE