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Lipid Metabolism Compound Library

カタログ番号 L2510
  ライブラリー構成化合物リスト   Excel SDF

Lipids are fatty acids and their derivatives, and substances related biosynthetically or functionally to these compounds. Lipids are commonly subdivided into four main groups: fatty acids (saturated and unsaturated), glycerides (glycerol-containing lipids), nonglyceride lipids (sphingolipids, steroids, waxes), and complex lipids (lipoproteins). Like the other large biological molecules, lipids perform many different functions in a cell. Lipids are critical for cell structure, function, and energy, as well as organs and body insulation and protection. Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown or storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes. Lipids metabolites are extremely essential for a wide range of cellular communication and metabolism. 

Numerous studies have shown that lipid metabolism plays an important role in the pathogenesis of a wide range of chronic diseases such as cardiovascular disease, aging, and cancer, etc. Lipid metabolism has now been accepted as a major metabolic pathway that is involved in many aspects of cancer cell biology. Discovering novel mechanisms of the lipid role in diseases and new ways to exploit these mechanisms for the optimal drug design would be beneficial for the prevention and treatment of these diseases.

TargetMol’s Lipid Metabolism Compound Library collects 492 compounds acting on key targets related to lipid metabolism, such as Acetyl-CoA Carboxylase、Acyltransferase、cholesteryl ester transfer protein (CETP)、FAAH、Fatty Acid Synthase (FASN)、HMG-CoA Reductase (HMGCR), etc. It is a powerful tool that can be used in lipid metabolism related drug development and mechanism studies.

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パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
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製品概要

  • 脂質代謝に関連する492化合物を独自に収集したライブラリーで、ハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • ターゲットにはアセチルCoAカルボキシラーゼ、アシルトランスフェラーゼ、コレステリルエステル転送タンパク質(CETP)、FAAH、脂肪酸シンターゼ(FASN)、HMG-CoAレダクターぜ(HMGCR)など
  • 化合物の概要、化学構造、標的、生物活性など詳細な情報を提供
  • NMRとHPLCにより高純度と高品質を担保

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L2510)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

PPAR (98)
Autophagy (95)
Apoptosis (62)
Phospholipase (38)
Endogenous Metabolite (36)
AMPK (36)
Lipoxygenase (36)
COX (35)
Antibacterial (27)
FAAH (26)
P450 (23)
Fatty Acid Synthase (22)
HMG-CoA Reductase (20)
Ferroptosis (20)
FXR (20)
ROS (20)
Retinoid Receptor (19)
Phosphatase (19)
Dehydrogenase (16)
Reactive Oxygen Species (16)
NF-κB (14)
Acyltransferase (14)
Lipase (12)
Acetyl-CoA Carboxylase (11)
Antifungal (11)
Liver X Receptor (10)
ROR (10)
Mitophagy (10)
Mitochondrial Metabolism (9)
Parasite (8)
PARP (8)
Isocitrate Dehydrogenase (IDH) (8)
Stearoyl-CoA Desaturase (SCD) (8)
ATP Citrate Lyase (7)
Akt (7)
Influenza Virus (7)
Potassium Channel (7)
Antibiotic (7)
Wnt/beta-catenin (7)
PKM (7)
NADPH (7)
Prostaglandin Receptor (6)
Estrogen/progestogen Receptor (5)
NADPH-oxidase (5)
CETP (5)
AChR (5)
TRP/TRPV Channel (5)
Calcium Channel (5)
Cannabinoid Receptor (5)
Epoxide Hydrolase (5)
Sirtuin (5)
Phosphorylase (5)
Reductase (5)
HSV (4)
Virus Protease (4)
Lipid (4)
TNF (3)
Transferase (3)
PDE (3)
Estrogen Receptor/ERR (3)
Chloride channel (3)
SIK (3)
DNA/RNA Synthesis (3)
Glutathione Peroxidase (3)
NPC1L1 (3)
Tyrosinase (3)
MAGL (3)
VEGFR (3)
Leukotriene Receptor (3)
SARS-CoV (3)
transporter (3)
MMP (3)
Proton pump (3)
RSV (2)
GPR (2)
Interleukin (2)
TGF-beta/Smad (2)
STAT (2)
c-Met/HGFR (2)
PI3K (2)
GPCR19 (2)
Nrf2 (2)
IL Receptor (2)
BCL (2)
PGC-1α (2)
Glucocorticoid Receptor (2)
GABA Receptor (2)
JNK (2)
p53 (2)
HIF/HIF Prolyl-Hydroxylase (2)
Caspase (2)
Anti-infection (2)
S1P Receptor (1)
ROS Kinase (1)
GST (1)
HIV Protease (1)
Thrombin (1)
TAM Receptor (1)
Ras (1)
YAP (1)
c-Kit (1)
Monocarboxylate transporter (1)
ribosome (1)
FLT (1)
Adenylyl cyclase (1)
c-RET (1)
HIF (1)
Aromatase (1)
Hydroxylase (1)
IκB/IKK (1)
HCV Protease (1)
5-HT Receptor (1)
Tyrosine Kinases (1)
EGFR (1)
Antioxidant (1)
Adrenergic Receptor (1)
FABP (1)
UGT (1)
FLAP (1)
iGluR (1)
Immunology/Inflammation related (1)
IAP (1)
ERK (1)
Gamma-secretase (1)
PKC (1)
Melatonin Receptor (1)
Cysteine Protease (1)
Serine Protease (1)
ABC (1)
PKA (1)
HBV (1)
LDL (1)
CDK (1)
Trk receptor (1)
DNA (1)
LTR (1)
Adenosine Receptor (1)
AChE (1)
RAR/RXR  (1)
SGLT (1)
Androgen Receptor (1)
Histone Demethylase (1)
CaMK (1)
Drug Metabolite (1)
PERK (1)
RAAS (1)
PAK (1)
Histamine Receptor (1)
Opioid Receptor (1)
GSK-3 (1)
Glucosidase (1)
Proteasome (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE