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Methylation Compound Library

カタログ番号 L3510
  ライブラリー構成化合物リスト   Excel SDF

Methylation is an important way of protein and nucleic acid modification that regulates gene expression and is closely related to many diseases such as cancer, aging, and Alzheimer's disease. It is an important field of study in epigenetics. The most common methylation modifications are DNA methylation and histone methylation

DNA methylation, the addition of methyl groups to DNA, was one of the first methylation modifications discovered. The modification occurs specifically at the CpG site, where cytosine is attached to guanylate via phosphate. Numerous studies have shown that DNA methylation can cause changes in chromatin structure, DNA conformation, DNA stability and the way DNA interacts with proteins, thereby controlling gene expression.

Histone methylation refers to the methylation that occurs at the N-terminal arginine Arg(R) or lysine Lys(K) residues of H3 and H4 histones and is mediated and catalyzed by histone methyltransferases. Histone methylation mainly causes heterochromatin formation, gene imprinting, X chromosome inactivation and transcriptional regulation.

TargetMol Methylation Compound Library is a collection of 128 methylation-related compounds that can be used for research in epigenetics, differentiation, aging, cancer, and more.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • メチル化に関連する128化合物からなるHTSおよびHCSに最適なコレクション
  • ターゲットには、DNAメチルトランスフェラーぜ、ヒストンメチルトランスフェラーぜなどをカバー
  • エピジェネティクス、細胞分化、アンチエイジング、がんなどの研究分野に最適
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • NMRおよびHPLCにより高純度と高品質を担保
  • ライブラリーの化合物は個別に提供可能

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L3510)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Histone Methyltransferase (84)
Histone Demethylase (26)
Apoptosis (17)
DNA Methyltransferase (15)
Autophagy (12)
Epigenetic Reader Domain (11)
JAK (3)
Histamine Receptor (3)
P450 (2)
Endogenous Metabolite (2)
HSV (2)
Monoamine Oxidase (2)
MAO (2)
Nucleoside Antimetabolite/Analog (2)
Parasite (2)
Tyrosine Kinases (1)
Antibiotic (1)
Ras (1)
Antifungal (1)
Sodium Channel (1)
AChR (1)
TNF (1)
Phosphatase (1)
Virus Protease (1)
5-HT Receptor (1)
HDAC (1)
Nrf2 (1)
Influenza Virus (1)
Glucocorticoid Receptor (1)
Histone Acetyltransferase (1)
SARS-CoV (1)
PGE Synthase (1)
Antibacterial (1)
Androgen Receptor (1)
Estrogen/progestogen Receptor (1)
Antifolate (1)
Calcium Channel (1)
DNA Alkylation (1)
Mitochondrial Metabolism (1)
DUB (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE