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PBCRBS Traditional Chinese Medicine Compound Library

カタログ番号 L6750
  ライブラリー構成化合物リスト   Excel SDF

The concept of “Promoting Blood Circulation for Removing Blood Stasis” (PBCRBS) is an important theory and therapeutic principle in traditional Chinese medicine (TCM). Common traditional Chinese medicines for PBCRBS include Ligusticum chuanxiong, Persica, Boswellia, and Myrrha, etc. These herbs are often characterized by pungent (xin), bitter (ku), and warm (wen) properties, allowing them to invigorate blood circulation and dispel stasis, exhibiting PBCRBS. Modern pharmacological research has shown that traditional Chinese medicines for PBCRBS have effects of improving hemodynamic abnormalities, hemorheological abnormalities, microcirculation disorders; resisting thrombosis, atherosclerosis, myocardial ischemia; inhibiting tissue abnormal proliferation, tumor growth; and shows analgesic effects. They are widely used in the treatment of cardiovascular and cerebrovascular diseases, diabetes, cirrhosis, and other conditions, demonstrating significant clinical efficacy and showing promising application.

Traditional Chinese medicines have multiple components and targets. The active components of a single TCM are diverse and each has different functions. An active component can influence multiple pathways. For example, curcumin, an active component of turmeric, can treat atrial fibrillation (AF) in rats by affecting the interleukin-17 (IL-17) signaling pathway. It can also exert neuroprotective effects in rats by activating the cyclic AMP response element-binding protein (CREB)/brain-derived neurotrophic factor (BDNF) signaling pathway.

To study the main active components and their mechanisms of action in PBCRBS TCMs, TargetMol has curated a library called “PBCRBS Traditional Chinese Medicine Compound Library” which consists of 580 compounds.

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パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
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Product discription

  • A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
  • Compounds sourced from over 40 TCMs with blood circulation-promoting and blood stasis-removing effects, including safflower, turmeric, Garden Balsam Seed, myrrh, etc.
  • With diverse structures, encompassing terpenes, alkaloids, flavonoids, and other structurally diverse compounds.
  • Detailed compound information on structures, targets, IC50 and activity descriptions.
  • NMR and HPLC/LCMS validated to ensure high purity and quality.
  • Comprehensive instructions on product handling, solvent selection, storage methods and concentration choice for initial screening.

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梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L6750)

Publications Cited TargetMol Libraries

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化合物ライブラリー情報実例

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ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
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