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Targeted Therapy Drug Library

カタログ番号 L2152
  ライブラリー構成化合物リスト   Excel SDF

Targeted therapy for cancer is a treatment modality at the cellular molecular level that targets a known cancer-causing site. Common targeted drugs include small molecule drugs and monoclonal antibodies. Monoclonal antibodies have higher selectivity but are large molecule proteins, which are difficult to enter cells, and their targets are often limited to the cell surface; small molecule drugs are advantageous for targeting molecules inside tumor cells since they are small enough to easily enter tumor cells and directly target the molecules inside. With high specificity and less toxic side effects, targeted drugs have remarkable therapeutic efficacy on a variety of malignant tumors. They have become the new mainstream antitumor drugs in the last decade.

TargetMol collected 119 tumor-targeted drugs and formed the Targeted Therapy Drug Library, a powerful tool in oncotherapy research.

TargetMolの製品は全て研究用試薬です。人体にはご使用できません。 また、個人の方への販売は行っておりません。
パッケージサイズ
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at [email protected]
ライブラリ構成化合物リストを依頼する
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製品概要

  • 分子標的薬である119種類の化合物を厳選した独自のコレクションで、ハイスループットスクリーニング(HTS)およびハイコンテンツスクリーニング(HCS)に最適
  • 非臨床試験および臨床試験において生物活性と安全性が確認済み
  • 腫瘍形成のメカニズム研究および抗がん薬物スクリーニングのツールとして効果的
  • 主要なターゲットとして、EGFR、VEGFR、c-Met、Bcr-Abl、HER2をカバー
  • 全化合物において高い生物活性、安全性、バイオアベイラビリティが報告ずみ
  • 化合物の概要、化学構造、標的、IC50値、生物活性など詳細な情報を提供
  • NMRとHPLC/LCMSにより高純度と高品質を担保し、偽陽性のリスクを低減

ライブラリーのカスタマイズ

TargetMol社化合物ライブラリーは自由にカスタマイズできます! もっと詳しく

梱包・保管

  • バーコード付き貯蔵管や96/384-wellプレートに入っている粉末固体またはDMSO溶液
  • ブルーアイス同梱にて出荷
ライブラリ構成化合物複合リストをリクエスト (L2152)

Publications Cited TargetMol Libraries

隠し

ライブラリーの構成

Autophagy (49)
Apoptosis (35)
c-Kit (23)
VEGFR (22)
PDGFR (19)
EGFR (14)
FLT (11)
FGFR (10)
Bcr-Abl (9)
Src (7)
c-RET (7)
Mitophagy (6)
Raf (6)
MEK (6)
ALK (6)
PI3K (5)
CDK (5)
c-Met/HGFR (5)
Tyrosine Kinases (5)
HDAC (4)
JAK (4)
HER (4)
PARP (4)
Ferroptosis (4)
c-Fms (3)
Trk receptor (3)
mTOR (3)
Androgen Receptor (3)
BTK (3)
ROS (3)
ROS Kinase (3)
Hedgehog/Smoothened (3)
Aromatase (3)
TAM Receptor (3)
Proteasome (3)
Estrogen/progestogen Receptor (2)
IGF-1R (2)
IRE1 (2)
Isocitrate Dehydrogenase (IDH) (2)
Dehydrogenase (2)
Smo (2)
Estrogen Receptor/ERR (2)
CSF-1R (2)
Microtubule Associated (1)
Retinoid Receptor (1)
P450 (1)
GABA Receptor (1)
NF-κB (1)
HIV Protease (1)
Ephrin Receptor (1)
Caspase (1)
Histone Methyltransferase (1)
ABC (1)
Ligands for Target Protein for PROTAC (1)
Virus Protease (1)
Antifolate (1)
Serine Protease (1)
ROCK (1)
MAPK (1)
PKC (1)
ERK (1)
DHFR (1)
HSP (1)
SARS-CoV (1)
ACK (1)
BCL (1)

化合物ライブラリー情報実例

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE