Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(+)-Afzelechin has a neuroprotective effect on the glutamate-induced neurotoxicity in HT22 cells, it has ABTS cation radical scavenging effects with IC50 values of 23.7 microM
説明 | (+)-Afzelechin has a neuroprotective effect on the glutamate-induced neurotoxicity in HT22 cells, it has ABTS cation radical scavenging effects with IC50 values of 23.7 microM |
ターゲット&IC50 | α-glucosidase:0.13 mM (ID50) |
In vitro | Antioxidant activity (AOA) assay-guided chemical analysis, using a rat pancreas homogenate model, of aerial parts from Eysenhardtia subcoriacea, led to isolation of the new compound subcoriacin (3-(2'-hydroxy-4',5'-methylendioxyphenyl)-6-(3''-hydroxymethyl-4''-hydroxybut-2''-enyl)-7-hydroxycoumarin) together with the known substances: (+)-catechin, (-)-epicatechin, (+)-Afzelechin, eriodictyol, (+)-catechin 3-O-beta-D-galactopyranoside and quercetin 3-O-beta-D-galactopyranoside as bioactive constituents. The structure of the compound was determined from 1D and 2D NMR spectroscopic analyses. Additional known constituents were characterized[1] |
植物由来 |
分子量 | 274.27 |
分子式 | C15H14O5 |
CAS No. | 2545-00-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(+)-Afzelechin 2545-00-8 Others (+) Afzelechin (+)Afzelechin Afzelechin Inhibitor inhibitor inhibit