Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME .
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 μg | 約 35 days | ¥ 53,000 |
50 μg | 約 35 days | ¥ 100,000 |
100 μg | 約 35 days | ¥ 182,000 |
250 μg | 約 35 days | ¥ 411,000 |
説明 | 5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME . |
分子量 | 320.473 |
分子式 | C20H32O3 |
CAS No. | 213126-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: >50 mg/mL (per Rao Maddipati)
Ethanol: >50 mg/mL (per Rao Maddipati)
PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE)
DMSO: >50 mg/mL (per Rao Maddipati)
You can also refer to dose conversion for different animals. 詳細
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(±)5(6)-DiHET lactone 213126-92-2 5(6)-DiHET lactone (±)5(6)DiHET lactone (±)5(6) DiHET lactone Inhibitor inhibitor inhibit