Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tartrate) is preferable to (R,S)-Anatabine for certain applications and formulations.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | お問い合わせ | ¥ 22,500 |
10 mg | お問い合わせ | ¥ 40,000 |
50 mg | お問い合わせ | ¥ 174,500 |
100 mg | お問い合わせ | ¥ 304,500 |
説明 | Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tartrate) is preferable to (R,S)-Anatabine for certain applications and formulations. |
In vitro | In vitro: Anatabine dose-dependently lowered Aβ1-40 and Aβ1-42 levels and reduced sAPPβ production without any effects on sAPPα levels. Anatabine lowered Aβ production by mainly impacting the β-cleavage of APP. Anatabine lowered NFκB activation. Anatabine inhibited BACE-1 transcription and reduced BACE-1 protein levels in human neuronal-like SHSY-5Y cells. (R,S)-Anatabine also dose-dependently inhibits NF-κB activation [1]. |
In vivo | In vivo: In a transgenic mouse model with AD, treatment with anatabine for 4 days remarkably lowered brain soluble Aβ1-40 and Aβ1-42 levels [1]. |
別名 | (R,S)-Anatabine (tartrate) |
分子量 | 310.3 |
分子式 | C10H12O2·C4H6O6 |
CAS No. | T23228 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20mg/ml
Ethanol: ≤1mg/mL
You can also refer to dose conversion for different animals. 詳細
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(R,S)-Anatabine (tartrate) (2743-90-0 free base) T23228 Others 2743-90-0 free base (R,S)Anatabine (tartrate) (2743900 free base) Anatabine (tartrate) Anatabine 2743-90-0 (R,S) Anatabine (tartrate) (2743 90 0 free base) (R,S)-Anatabine (tartrate) Inhibitor inhibitor inhibit