Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 226,500 |
50 mg | 約10-14 週間 | ¥ 312,500 |
100 mg | 約10-14 週間 | ¥ 503,000 |
説明 | (Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1]. |
ターゲット&IC50 | 11β-HSD1 (human):10 nM , 11β-HSD1 (mouse):68 nM |
In vivo | (Rac)-BMS-816336 (compound 6n) demonstrates high metabolic stability, as evidenced by its retention rates of 88%, 82%, and 72% in human, mouse, and rat models, respectively [1]. |
分子量 | 341.44 |
分子式 | C21H27NO3 |
CAS No. | T12663 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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(Rac)-BMS-816336 T12663 Metabolism Dehydrogenase BMS 816336 BMS-816336 (Rac)BMS816336 (Rac) BMS 816336 BMS816336 Inhibitor inhibitor inhibit