Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。
説明 | (E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。 |
In vitro | (E/Z)-BIO-acetoxime (compound 13) demonstrates a selectivity greater than 200-fold for GSK-3α/β over CDK5/p25, CDK2/cyclin A, and CDK1/cyclin B, exhibiting IC50 values of 0.01, 2.4, 4.3, and 63 μM, respectively [1]. |
分子量 | 398.21 |
分子式 | C18H12BrN3O3 |
CAS No. | 740841-15-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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(E/Z)-BIO-acetoxime 740841-15-0 Inhibitor inhibitor inhibit