Powder: -20°C for 3 years | In solvent: -80°C for 1 year
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 μM. (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 μM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
500 μg | 約 35 days | ¥ 18,000 |
1 mg | 約 35 days | ¥ 33,000 |
5 mg | 約 35 days | ¥ 132,000 |
10 mg | 約 35 days | ¥ 209,500 |
説明 | The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 μM. (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 μM. |
分子量 | 317.18 |
分子式 | C16H13BrO2 |
CAS No. | 478288-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 0.05 mg/mL
DMSO: 25 mg/mL
Ethanol: 5 mg/mL
DMF: 50 mg/mL
You can also refer to dose conversion for different animals. 詳細
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(R)-Bromoenol lactone 478288-90-3 (R) Bromoenol lactone Bromoenol lactone (R)Bromoenol lactone Inhibitor inhibitor inhibit