Powder: -20°C for 3 years | In solvent: -80°C for 1 year
β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively.
説明 | β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively. |
In vitro | 'β-catenin-IN-37 exhibits affinity for the β-catenin/Tcf protein-protein interaction (PPI), demonstrating dissociation constants (K_i values) of 17 μM and 18 μM in fluorescence polarization (FP) assay and AlphaScreen assay, respectively[1].' |
分子量 | 307.277 |
分子式 | C13H9N9O |
CAS No. | 1783856-40-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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β-catenin-IN-37 1783856-40-5 βcateninIN37 b-catenin-IN-37 beta-catenin-IN-37 β catenin IN 37 Inhibitor inhibitor inhibit