Powder: -20°C for 3 years | In solvent: -80°C for 1 year
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 μg | 約 35 days | ¥ 88,000 |
50 μg | 約 35 days | ¥ 166,500 |
100 μg | 約 35 days | ¥ 312,500 |
説明 | 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids. |
分子量 | 318.45 |
分子式 | C20H30O3 |
CAS No. | 116180-17-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
0.1 M Na2CO3: 2 mg/mL
DMF: Miscible
DMSO: Miscible
PBS (pH 7.2): 0.8 mg/mL
Ethanol: Miscible
You can also refer to dose conversion for different animals. 詳細
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12(S)-HEPE 116180-17-7 12(S)HEPE 12HEPE 12(S) HEPE Inhibitor inhibitor inhibit