Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 μM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 μg | 約 35 days | ¥ 25,500 |
50 μg | 約 35 days | ¥ 48,500 |
100 μg | 約 35 days | ¥ 89,000 |
500 μg | 約 35 days | ¥ 390,500 |
説明 | Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 μM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation. |
分子量 | 324.505 |
分子式 | C20H36O3 |
CAS No. | 519038-92-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 10 mg/mL
PBS (pH 7.2): 0.5 mg/mL
DMSO: 10 mg/mL
Ethanol: 50 mg/mL
You can also refer to dose conversion for different animals. 詳細
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14,15-EE-5(Z)-E 519038-92-7 14,15-EE-5E 14,15EE5(Z)E 14,15 EE 5(Z) E Inhibitor inhibitor inhibit