Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 42,000 |
5 mg | 約 35 days | ¥ 182,000 |
10 mg | 約 35 days | ¥ 328,500 |
説明 | Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid. |
別名 | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide |
分子量 | 441.612 |
分子式 | C27H39NO4 |
CAS No. | 1138395-10-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 25 mg/mL
PBS (pH 7.2): 0.25 mg/mL
Ethanol: 50 mg/mL
DMSO: 25 mg/mL
Acetonitrile: 3 mg/mL
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide 1138395-10-4 Others 17phenyl trinor Prostaglandin F2α cyclopropyl methyl amide 17-phenyl trinor Prostaglandin F-2α cyclopropyl methyl amide 17 phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Inhibitor inhibitor inhibit