Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that not only inhibits DNA-dependent RNA polymerases I and II, but also competitively and strongly inhibits the incorporation of UTP into RNA, exhibiting a Ki value of 2.0 μM[1].
説明 | 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that not only inhibits DNA-dependent RNA polymerases I and II, but also competitively and strongly inhibits the incorporation of UTP into RNA, exhibiting a Ki value of 2.0 μM[1]. |
In vitro | 3'-Deoxyuridine-5'-triphosphate (3'-dUTP), efficiently synthesized from cordycepin, is a potent competitive inhibitor of UTP incorporation into RNA by RNA polymerases. Its lack of effect on poly (rA) synthesis suggests its utility in dissecting the nuances of template and substrate relationships within RNA synthesis processes, particularly in contexts involving chromatin, isolated nuclei, or permeable cells[1]. |
分子量 | 468.14 |
分子式 | C9H15N2O14P3 |
CAS No. | 69199-40-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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3'-Deoxyuridine-5'-triphosphate 69199-40-2 3'Deoxyuridine5'triphosphate 3' Deoxyuridine 5' triphosphate Inhibitor inhibitor inhibit