Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 μg | 約 35 days | ¥ 28,500 |
50 μg | 約 35 days | ¥ 53,000 |
100 μg | 約 35 days | ¥ 99,000 |
250 μg | 約 35 days | ¥ 218,000 |
説明 | 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM. |
分子量 | 342.479 |
分子式 | C22H30O3 |
CAS No. | 845673-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 0.1 mg/mL
DMF: 50 mg/mL
DMSO: 50 mg/mL
Ethanol: 50 mg/mL
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
4-oxo Docosahexaenoic Acid 845673-74-7 4 oxo Docosahexaenoic Acid 4oxo Docosahexaenoic Acid Inhibitor inhibitor inhibit