Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約6-8 週間 | ¥ 68,500 |
25 mg | 約6-8 週間 | ¥ 226,500 |
50 mg | 約6-8 週間 | ¥ 312,500 |
100 mg | 約6-8 週間 | ¥ 427,000 |
説明 | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM). |
ターゲット&IC50 | CDK5-p25:20 nM, CDK1-CyclinB:25 nM, GSK-3β:9 nM |
分子量 | 403.17 |
分子式 | C16H10IN3O2 |
CAS No. | 331467-03-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 66.7 mg/mL (165.43 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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5-Iodo-indirubin-3'-monoxime 331467-03-9 Cell Cycle/Checkpoint PI3K/Akt/mTOR signaling Stem Cells GSK-3 CDK Glycogen synthase kinase-3 5Iodoindirubin3'monoxime Inhibitor Glycogen synthase kinase 3 Cyclin dependent kinase 5 Iodo indirubin 3' monoxime inhibit inhibitor