Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase with antioxidant property.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 7,500 | |||
25 mg | 在庫あり | ¥ 13,000 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 32,500 | |||
200 mg | 在庫あり | ¥ 48,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | 5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with IC50 of about 30 μM. 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase with antioxidant property. |
ターゲット&IC50 | K+-ATP channel:30 μM |
In vitro | The treatment of 5-Hydroxydecanoate sodium abolished the beneficial effects of penehyclidine hydrochloride (PHC) preconditioning in anoxia/reoxygenation (A/R)‐induced injury in H9c2 cells. 5-Hydroxydecanoate sodium blocked the inhibitory effect of PHC on Ca2+ overload and ROS production and promoted the release of Cyt-C from mitochondria into cytoplasm. 5-Hydroxydecanoate sodium attenuated the anti-apoptotic effect of PHC[1]. |
In vivo | The treatment of 5-Hydroxydecanoate sodium (100 μM) abolished the effects of ischemic preconditioning (IPC) on the contractile recovery, but 5-Hydroxydecanoate sodium did not affect its effect on the contracture, lactate production, glycogenolysis and viable tissue in rats[2]. |
分子量 | 210.25 |
分子式 | C10H19NaO3 |
CAS No. | 71186-53-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.6 mg/mL (17.12 mM)
You can also refer to dose conversion for different animals. 詳細
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5-Hydroxydecanoate sodium 71186-53-3 Membrane transporter/Ion channel Potassium Channel 5 Hydroxydecanoate sodium 5Hydroxydecanoate sodium Inhibitor inhibitor inhibit