Powder: -20°C for 3 years | In solvent: -80°C for 1 year
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3
説明 | 9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3 |
In vivo | In vivo, 9(S),12(S),13(S)-TriHOME (1 g/animal) enhances the antiviral IgA and IgG antibody responses induced by a nasal influenza hemagglutinin (HA) vaccine by 5.2- and 2-fold, respectively, in mice.4 |
分子量 | 330.46 |
分子式 | C18H34O5 |
CAS No. | 97134-11-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
You can also refer to dose conversion for different animals. 詳細
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9(S),12(S),13(S)-TriHOME 97134-11-7 9,12,13TriHOME 9(S),12(S),13(S) TriHOME 9(S),12(S),13(S)TriHOME Inhibitor inhibitor inhibit