Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA)-induced chloride current, the potentiating action of aflatrem on the GABAA receptor channel may explain the initial symptoms of intoxication caused by aflatrem in vivo.
説明 | Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA)-induced chloride current, the potentiating action of aflatrem on the GABAA receptor channel may explain the initial symptoms of intoxication caused by aflatrem in vivo. |
分子量 | 501.667 |
分子式 | C32H39NO4 |
CAS No. | 70553-75-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aflatrem 70553-75-2 Membrane transporter/Ion channel Neuroscience GABA Receptor Inhibitor inhibitor inhibit