Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 624,500 |
50 mg | 約10-14 週間 | ¥ 822,000 |
100 mg | 約10-14 週間 | ¥ 1,124,500 |
説明 | BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia. |
ターゲット&IC50 | FFA1/GPR40:0.07 µM (IC50) |
別名 | BMS 986118 |
分子量 | 540.96 |
分子式 | C25H28ClF3N4O4 |
CAS No. | 1610562-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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BMS-986118 1610562-74-7 BMS986118 BMS 986118 Inhibitor inhibitor inhibit