store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Braco-19 is a telomerase/telomere inhibitor with anti-HIV-1 activity.Braco-19 is a quaternary (GQ)-binding ligand that inhibits tumor growth and inhibits apoptosis.Braco-19 is also a HAdV viral replication inhibitor and is used in the study of HIV infections and human herpesvirus infections.
説明 | Braco-19 is a telomerase/telomere inhibitor with anti-HIV-1 activity.Braco-19 is a quaternary (GQ)-binding ligand that inhibits tumor growth and inhibits apoptosis.Braco-19 is also a HAdV viral replication inhibitor and is used in the study of HIV infections and human herpesvirus infections. |
In vitro | In HEK 293 cells, Braco-19 (20 μM; 40 μM; 24 hours) displayed low cytotoxicity and decreased the eGFP fluorescence[1]. |
In vivo | In nude mice bearing established UXF1138LX xenografts, Braco-19 (2 mg/kg; intraperitoneal injection; 3 weeks; starting 6 days after transplantation of UXF1138LX fragments) exhibited partial tumor regression, with an optimal T/C of 4.1% on day 28, representing a 95.9% inhibition of tumor growth compared to the control[1]. |
分子量 | 593.76 |
分子式 | C35H43N7O2 |
CAS No. | 351351-75-2 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (33.68 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Braco-19 351351-75-2 Apoptosis DNA Damage/DNA Repair Microbiology/Virology Proteases/Proteasome HIV Protease Telomerase Braco19 Braco 19 Inhibitor inhibitor inhibit