store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,000 | |||
5 mg | 在庫あり | ¥ 26,000 | |||
10 mg | 在庫あり | ¥ 43,500 | |||
25 mg | 在庫あり | ¥ 95,000 | |||
50 mg | 在庫あり | ¥ 156,000 | |||
100 mg | 在庫あり | ¥ 259,500 |
説明 | Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication. |
In vitro | The IC50 for BRACO-19 trihydrochloride (1.0-10 μM) in UXF1138L cells is 2.5 μM, the IC100 is 5 μM. BRACO-19 trihydrochloride (1 μM) dramatically reduces the expression of nuclear hTERT[3]. BRACO-19 trihydrochloride (0-40 μM) dose-dependently decreases the AdV virus growth in eGFP-transinfected HEK 293 cells. BRACO-19 trihydrochloride (0-150 μM) decreases band intensity in an increasing concentration-dependent manner[4]. |
In vivo | In nude mice established UXF1138LX Xenografts, BRACO-19 trihydrochloride (2 mg/kg; i.p.) significantly inhibits tumor growth and shows marked single-agent antitumor activity. some animals in the group shows complete regressions (5 of 12 tumors)[3]. |
別名 | BRAC-O19, BRACO19 hydrochloride, BRACO19 3HCl, BRACO 19, BRACO19 HCl |
分子量 | 703.14 |
分子式 | C35H46Cl3N7O2 |
CAS No. | 1177798-88-7 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 19.8 mg/mL (28.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Braco-19 trihydrochloride 1177798-88-7 DNA Damage/DNA Repair Telomerase Braco-19 BRACO19 BRAC-O19 BRACO19 hydrochloride BRACO19 3HCl BRACO19 Hydrochloride BRACO 19 BRACO-19 Hydrochloride BRACO19 HCl Braco-19 Trihydrochloride BRACO 19 Hydrochloride Inhibitor inhibitor inhibit