Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
In vitro | The primary action of CMLD012612 hinges on its interaction with eIF4A1, as demonstrated by eIF4A1em1jp cells exhibiting at least a 10-fold increased resistance compared to the original NIH/3T3 cells. This resistance is diminished at higher concentrations of CMLD012612, possibly because of the presence of wild-type eIF4A2 in the eIF4A1em1jp cells. |
分子量 | 559.61 |
分子式 | C31H33N3O7 |
CAS No. | 2368900-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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CMLD012612 2368900-35-8 Others CMLD 012612 CMLD-012612 Inhibitor inhibitor inhibit