Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.
パッケージサイズ | 在庫状況 | 単価(税別) | |
---|---|---|---|
1 mg | 在庫あり | ¥ 52,500 | |
5 mg | 在庫あり | ¥ 131,500 | |
10 mg | 在庫あり | ¥ 189,000 | |
25 mg | 在庫あり | ¥ 287,000 | |
50 mg | 在庫あり | お問い合わせ |
In vivo | PF-06647263 (0.27, 0.36 mg/kg) significantly induces tumor regression in TNBC xenografts. An ADC, which is a conjugate of a humanized anti-EFNA4 monoclonal antibody and the DNA-damaging agent calicheamicin, demonstrates sustained tumor regressions in TNBC and ovarian cancer PDX models in vivo [1]. |
別名 | Calicheamicin γ1 |
分子量 | 1368.35 |
分子式 | C55H74IN3O21S4 |
CAS No. | 108212-75-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (73.08 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Calicheamicin 108212-75-5 Others ADC Cytotoxin Calicheamicin r1 Bacterial Inhibitor Apoptosis inhibit ADC Payload Calicheamicin gamma1 Calicheamicin γ 1 DNA Alkylator/Crosslinker Calicheamicin γ-1 Calicheamicin γ1 Antibiotic inhibitor