Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis.
説明 | Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis. |
別名 | Ceralasertib, AZD-6738, AZD 6738, AZD6738 |
分子量 | 458.54 |
分子式 | C21H26N6O4S |
CAS No. | 1352280-98-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Ceralasertib formate 1352280-98-8 Ceralasertib AZD-6738 Ceralasertib Formate AZD 6738 AZD6738 Inhibitor inhibitor inhibit