Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against HL-60 cell lines.
説明 | Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against HL-60 cell lines. |
In vitro | The cytotoxicity of Desacetylcinobufotalin (DEBF) and apoptosis induced by DEBF was measured. Additionally the mechanism of Apoptosis induced by DEBF was studied through Western blot. The results show DEBF displayed the marked inhibition effect to HepG2 cells and the IC50 value is 0.0279μmol/ml. The expression of Bax was significantly increased and the expression of Bcl-2 was markedly decreased, compared to the control[1] |
分子量 | 416.51 |
分子式 | C24H32O6 |
CAS No. | 4099-30-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Desacetylcinobufotalin 4099-30-3 Others Inhibitor inhibitor inhibit