Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
5 mg | 約4-6 週間 | ¥ 17,500 |
10 mg | 約4-6 週間 | ¥ 26,500 |
25 mg | 約4-6 週間 | ¥ 54,000 |
50 mg | 約4-6 週間 | ¥ 93,000 |
100 mg | 約4-6 週間 | ¥ 149,000 |
1 mL * 10 mM (in DMSO) | 約4-6 週間 | ¥ 38,000 |
説明 | Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4. |
ターゲット&IC50 | VEGFR1-4 (Class V):8-13 nM, FGFR1/3 (Class IV):8-13 nM, c-Kit (class III):2 nM, FLT3 (class III):1 nM |
別名 | Dovitinib (TKI-258) Dilactic Acid, TKI258 Dilactic acid |
分子量 | 572.59 |
分子式 | C21H21FN6O·2C3H6O3 |
CAS No. | 852433-84-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83 mg/mL (145 mM)
H2O: 64 mg/mL (111.8 mM)
Ethanol: <1 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Dovitinib Dilactic Acid 852433-84-2 Angiogenesis Tyrosine Kinase/Adaptors FLT VEGFR FGFR c-Kit Dovitinib (TKI-258) Dilactic Acid TKI258 Dilactic acid Inhibitor inhibitor inhibit