store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 89,500 |
2 mg | 在庫あり | ¥ 134,500 |
5 mg | 在庫あり | ¥ 206,000 |
10 mg | 在庫あり | ¥ 302,000 |
25 mg | 在庫あり | ¥ 453,000 |
50 mg | 在庫あり | ¥ 633,500 |
説明 | Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii. |
ターゲット&IC50 | KPC2 (Class A):4 nM , OXA24 (Class D):190 nM , AmpC (Class C):14 nM |
In vitro | Durlobactam sodium salt exhibited antibacterial activity against Enterobacteriaceae including E. coli, Klebsiella pneumoniae, Enterobacter cloacae, Stenotrophomonas maltophilia and Citrobacter species. Durlobactam sodium salt was also active against colistin-resistant E. coli isolates bearing the mcr-1 plasmid[1]. |
In vivo | Sulbactam–Durlobactam in thigh and lung murine infection models showed a dose-dependent reduction in MDR A. baumannii bacterial counts[1]. |
別名 | ETX2514 sodium salt |
分子量 | 299.23 |
分子式 | C8H10N3NaO6S |
CAS No. | 1467157-21-6 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 2.5 mg/mL (8.35 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Durlobactam sodium salt 1467157-21-6 Microbiology/Virology Antibacterial ETX-2514 ETX2514 sodium salt ETX 2514 Durlobactam sodium Inhibitor inhibitor inhibit