Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epelsiban is a selective and orally bioavailable oxytocin receptor antagonist (pKi: 9.9 for human oxytocin receptor).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 486,500 |
50 mg | 約8-10 週間 | ¥ 638,000 |
100 mg | 約8-10 週間 | ¥ 849,500 |
ターゲット&IC50 | OTR (human):(pKi)9.9 , OTR (human):192 nM |
In vivo | Epelsiban exhibits low intrinsic clearance in rat, dog, and cynomolgus monkey microsomes, demonstrating good bioavailability (55%) while showing no genotoxic effects, and maintaining a satisfactory safety profile when orally administered to female rats. Additionally, Epelsiban effectively inhibits the oxytocin receptor in rats with an IC50 of 192 nM. |
別名 | GSK 557296 |
分子量 | 518.65 |
分子式 | C30H38N4O4 |
CAS No. | 872599-83-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Epelsiban 872599-83-2 Others GSK 557296 GSK-557296 GSK557296 Inhibitor inhibitor inhibit