Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
説明 | HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS. |
ターゲット&IC50 | HPGDS:(kd)0.8 μM, HPGDS:6 μM |
In vitro | HQL-79 is a competitive inhibitor against substrate PGH2. HQL-79 is also a non-competitive one against GSH[1]. |
分子量 | 377.48 |
分子式 | C22H27N5O |
CAS No. | 162641-16-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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HQL-79 162641-16-9 Others HQL 79 HQL79 Inhibitor inhibitor inhibit