Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ipatasertib is an orally active, potent and selective Akt inhibitor with antitumor activity. Inhibition of Akt activity by Ipatasertib resulted in blockade of cell-cycle progression and reduced viability of cancer cell lines. Markers of Akt activation, including high-basal phospho-Akt levels, PTEN loss, and PIK3CA kinase domain mutations, correlate with sensitivity to Ipatasertib.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Ipatasertib is an orally active, potent and selective Akt inhibitor with antitumor activity. Inhibition of Akt activity by Ipatasertib resulted in blockade of cell-cycle progression and reduced viability of cancer cell lines. Markers of Akt activation, including high-basal phospho-Akt levels, PTEN loss, and PIK3CA kinase domain mutations, correlate with sensitivity to Ipatasertib. |
別名 | GDC0068, RG 7440, GDC 0068, RG-7440, GDC-0068, RG7440 |
分子量 | 494.46 |
分子式 | C24H33Cl2N5O2 |
CAS No. | 1489263-16-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Ipatasertib HCl 1489263-16-2 GDC0068 RG 7440 GDC 0068 RG-7440 GDC-0068 RG7440 Inhibitor inhibitor inhibit